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The Analyst

Current research reports and chronological list of recent articles..




The Analyst is the scientific journal of choice for publishing urgent new work of the highest quality in analytical, bioanalytical and detection science.

The publisher is the Royal Society of Chemistry, UK. The copyright and publishing rights of specialized products listed below are in this publishing house. This is also responsible for the content shown.

To search this web page for specific words type "Ctrl" + "F" on your keyboard (Command + "F" on a Mac). Then: type the word you are searching for in the window that pops up!

Additional research articles see Current Chemistry Research Articles. Magazines with similar content (analytical chemistry):

 - Analytica Chimica Acta.

 - Analytical Chemistry.

 - Analytical and Bioanalytical Chemistry.



The Analyst - Abstracts



Cyanine dye-assembled composite upconversion nanoparticles for the sensing and cell imaging of nitrite based on a single particle imaging method

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00594H, Paper
Yunchun Liu, Wanru Zhu, Xinru Wei, Lun Wang, Hongqi Chen
In this work, a single particle imaging method based on the total internal reflection (TIR) imaging platform for the sensing and cell imaging of nitrite (NO2-) in the near-infrared region...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 19.05.2022


Determination of intracellular ascorbic acid using tandem mass spectrometry

Analyst, 2022, Advance Article
DOI: 10.1039/D1AN02160E, Communication
Chizumi Abe, Ohki Higuchi, Akira Matsumoto, Taiki Miyazawa
Ascorbic acid is involved in a variety of biological events.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 18.05.2022


Picomolar level Electrochemical Detection of Hydroquinone, Catechol and Resorcinol Simultaneously Using a MoS2 Nano-Flower Decorated Graphene

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00531J, Paper
Arya J. S Nair, Saisree S, K. Y. Sandhya
Herein, a graphene-nano-molybdenum disulphide (pGr-MoS2), synthesized from pulverized graphite and using precursors of MoS2, was investigated for the electrochemical sensing of dihydroxy benzene isomers (DHBI): hydroquinone (HQ), catechol (CA), and...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 18.05.2022


Solid-state Nanopore Analysis on Conformation Change of DNA Polymerase I induced by DNA Substrate

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00567K, Paper
Jiye Fu, Linlin Wu, Gang Hu, Fuyao Li, Qinyu Ge, Zuhong Lu, Jing Tu
Proteins with changeable conformation, such as polymerases, play a very important role in various life activities. Their conformational changes can be reflected in the structural size and flexibility, which may...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 18.05.2022


Microfluidic Flow Cytometry for Blood-Based Biomarker Analysis

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00283C, Critical Review
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Yuxin Zhang, Ying Zhao, Tim Cole, Jiahao Zheng, Qiaoge Bayin, Jinhong Guo, Shiyang Tang
Flow cytometry has proven its capability for rapid and quantitative analysis of individual cells and the separation of targeted biological samples from others. The emerging microfluidics technology makes it possible...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 18.05.2022


Combination of LIBS-based elemental analysis and near-infrared molecular fingerprinting of bile juice to enhance identification of gallbladder cancer

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00563H, Paper
Changhwan Eum, Eunjin Jang, Hyang Kim, Sang-Ho Nam, Yonghoon Lee, Dongho Choi, Hoeil Chung
Laser-induced breakdown spectroscopy (LIBS) and near-infrared (NIR) spectroscopy, enabling the measurement of raw bile directly without sample pretreatment, were cooperatively combined to enhance the discrimination of gallbladder cancer (GBC) from...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 17.05.2022


Ratiometric fluorescence enzyme-linked immunosorbent assay based on carbon dots@SiO2@CdTe quantum dots with dual functionalities for alpha-fetoprotein

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00691J, Paper
Xiuhui Liang, Zhenzhen Lin, Ling Li, Dianping Tang, Jinfeng Kong
Molecular tags such as fluorophores are increasingly being replaced with nanoparticles thanks to their superior optical properties, substantially chemical stability, and stability against photobleaching. Herein, we innovatively constructed a new...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 17.05.2022


A Fluorimetric Test Strip with Suppressed “Coffee Ring Effect” for Selective Mercury Ion Analysis

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00562J, Communication
Yuchun Qiao, Yu Fang, Jizhen Shang, Xiaoting Zhao, Shuai Li, Guo-Jiang Mao, Hua Wang
Nowadays, test strips have been widely applied but mostly limited to the qualitative or half-quantitative analysis of targets, for which one of the main reasons was the formidable “Coffee Ring...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 13.05.2022


PharmaChk: a decade of research and development towards the first quantitative, field-based medicine quality screening instrument

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00284A, Tutorial Review
Andrew J. Acevedo, Darash Desai, Muhammad H. Zaman, Gabriela Apiou-Sbirlea
We describe the scientific, engineering work over the first ten years of PharmaChk, the first quantitative, portable instrument for medicine quality screening, to illustrate what it takes for academic labs to translate observations into interventions.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 13.05.2022


Visible microspectrophotometry coupled with machine learning to discriminate the erythrocytic life cycle stages of P. Falciparum malaria parasites in functional single cells

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00274D, Paper
John Adeola Adegoke, Hannah Raper, Callum Gassner, Philip Heraud, Bayden Robert Wood
Malaria was regarded as the most devastating infectious disease of the 21st century until the COVID-19 pandemic. Asexual blood staged parasites (ABS) play a unique role in ensuring the parasite’s...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 12.05.2022


Photoelectrochemical sandwich immunoassay of CYFRA21-1 based on In2O3/WO3 type-II heterojunction and CdS quantum dots-polydopamine nanospheres labeling

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00522K, Paper
Luyao Liu, Chenglong Sun, Jialin Liu, Yun Du, Qingji Xie
Using an In2O3/WO3 type-II heterojunction modified fluorine-doped tin oxide (FTO) electrode as the photoanode and CdS quantum dots (QDs)-polydopamine nanospheres (PDA NSs) as the secondary antibody (Ab2) labeling, the photoelectrochemistry...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 11.05.2022


In vitro electrochemical measurement of serotonin release in the human jejunum mucosa using a diamond microelectrode

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00487A, Paper
Marion France, James J. Galligan, Greg M. Swain
We report herein on the use of a boron-doped diamond microelectrode (DME) to record oxidation currents in vitro associated with the release of serotonin from enterochromaffin cells in the epithelium of the human intestinal mucosa.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 11.05.2022


CLASSIFICATION OF BALLPOINT PEN INKS BASED ON SELECTIVE EXTRACTION AND SUBSEQUENT DIGITAL COLOR AND CLUSTER ANALYSES

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00482H, Paper
Andrey V Kalinichev, Anastasia V Kravchenko, Ivan P Gryazev, Arseniy A Kechin, Oleg R Karpukhin, Evgeniia M Khairullina, Ludmilla Kartsova, Anna G Golovkina, Vladimir A Kozynchenko, Maria A Peshkova, Ilya Tumkin
Here, we propose a novel approach to the classification of blue ballpoint pen inks based on a combination of selective extraction of coloring components from a paper carrier, digital color...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 11.05.2022


Plasmon Resonance-Inspired Discriminator Unscrambles Lipoprotein Subtypes

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00550F, Paper
Jianfang Cao, Mingshu Shuai, Yang Shu, Jian-Hua Wang
The cardiovascular diseases are tightly linked to circulating lipoprotein subtypes. While the significance for their discrimination is generally underappreciated. Herein, we designed a facile approach for efficacious and precise profiling...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 11.05.2022


Biophysical quantification of reorganization dynamics of human pancreatic islets during co-culture with adipose-derived stem cells

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00222A, Paper
Karina Torres-Castro, Mohammad S. Azimi, Walter B. Varhue, Carlos Honrado, Shayn M. Peirce, Nathan S. Swami
Reorganization dynamics of human islets during co-culture with adipose stem cells depends on islet size and the heterogeneity can be assessed based on biomechanical opacity of individual islets.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 11.05.2022


A novel ratiometric fluorescent and colorimetric sensor based on 1,8–naphthalimide derivative for nanomolar Cu2+ sensing: Smartphone and food applications

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00537A, Paper
Sukriye Nihan KARUK ELMAS, Fatma Nur Arslan, Duygu Aydin
A novel 1,8–naphthalimide–based chemical sensor 3-((2-(2-butyl-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-6-yl)hydrazone-o)methyl)-4-hydroxy-[1,1-biphenyl]-4-carbonitrile (BUDIN) with a ratiometric fluorescence behavior as well as ''naked–eye'' response was developed for sensitive and specific determination of Cu2+ in nanomolar level. With...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 10.05.2022


Point-of-care detection of sevoflurane anesthetics in exhaled breath using a miniature TOFMS for diagnosis of postoperative agitation symptoms in children

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00479H, Paper
Bing Liu, Wenxi Tang, Hang Li, Ruidong Liu, Fengshuo Dong, Yingzhe Guo, Jianjun Li, Keyong Hou
A miniature TOFMS with MEPEI has been developed for POC diagnosis of postoperative agitation symptoms, and can analyze sevoflurane by direct sampling. The risk is high when the sevoflurane in the exhaled breath is higher than 500 ppmv.
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Datum: 10.05.2022


A coumarin coupled tetraphenylethylene based multi-targeted AIEgen for cyanide ion and nitro explosive detection, and cellular imaging

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00040G, Paper
Viraj G Naik, Sharanabasava D Hiremath, Ankit Thakuri, Vijay Hemmadi, Malabika Biswas, Mainak Banerjee, Amrita Chatterjee
A coumarin coupled tetraphenylethylene based AIEgen (TPE-Lac) with intense greenish-yellow emission has been synthesized and utilized for multipurpose sensing and imaging applications. TPE-Lac acts as a sensitive sensor for the...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 10.05.2022


Plastic-based lateral flow immunoassay device for electrochemical detection of NT-proBNP

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00685E, Paper
Nikhil Raj, Richard M. Crooks
A low-cost plastic-based lateral flow device was developed to detect NT-proBNP, a heart failure marker, using the electrochemical metalloimmunoassay technique.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 09.05.2022


Cytidine-rich hydrogel as an electrochemical signal amplification strategy for microRNA detection

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00667G, Paper
Xinying Zhang, Zhiwei Zhang, Chujing Yang, Ziheng Hu, Yingying Chen, Lingyan Feng
This signal amplification strategy decreased the signal response while increasing the complex of the biosensors.
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Datum: 09.05.2022


A novel AIE fluorescent probe for the monitor of aluminum ion in living cells and zebrafish

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00543C, Paper
Yabing Gan, Guoxing Yin, Jianhua Wang, Peng Yin
A novel fluorescent probe BTD with aggregation induced emission (AIE) characteristics for the monitor of Al3+ was rationally developed. This probe could be used to detect Al3+ in aqueous...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 09.05.2022


A facile visualized solid-phase detection of virus-specific nucleic acid sequences through an upconversion activated linear luminescence recovery process

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00382A, Paper
Xiaorong Liu, Chaonan He, Qi Huang, Mengmeng Yu, Zhuang Qiu, Haoxin Cheng, Yifei Yang, Xian Hao, Xiaolei Wang
Based on the LRET between UCNPs and AuNPs, a solid-phase biosensor was developed for detection of virus-specific nucleic acid sequences by the naked eye, and is expected to become a fast, facile, efficient and reliable POCT platform.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 07.05.2022


Hybridizing aggregated gold nanoparticles with hydrogel to prepare flexible SERS chip for detecting organophosphorus pesticides

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00541G, Paper
Jiaxin Zhang, Xiajun Zhu, Mingming Chen, Tianwen Chen, Zhihong Liu, Jianli Huang, Fengfu Fu, Zhenyu Lin, Yongqiang Dong
Surface enhanced Raman scattering (SERS) is an ultrasensitive analytic technique. However, the application of SERS in quantitative analysis usually suffers from poor reliability due to the limitations of current developed...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 04.05.2022


Development and critical evaluation of a novel fluorescent nanosensor based on a molecularly imprinted polymer for the rapid detection of procymidone in ginseng

Analyst, 2022, Advance Article
DOI: 10.1039/D1AN02186A, Paper
Yi Huang, Nan Guo, Chaojian Xu, Ningkang Xie, Feiyan Liang, Shuo Yang, Shaowu Lv
Effective methods are required to quantify the organochlorine pesticide procymidone due to its potentially harmful effects toward human health and the environment.
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Datum: 04.05.2022


Highly sensitive and selective surface plasmon resonance biosensor for detection of SARS-CoV-2 spike S1 protein

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00426G, Paper
Qiong Wu, Wen Wu, Fangfang Chen, Ping Ren
The reality that the coronavirus disease 2019 (COVID-19) is still raging around the world and making a comeback with a strong posture has highlighted the need for rapid and sensitive...
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 04.05.2022


Tandem-trapped ion mobility spectrometry/mass spectrometry (tTIMS/MS): a promising analytical method for investigating heterogenous samples

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00335J, Critical Review
Fanny C. Liu, Mark E. Ridgeway, Melvin A. Park, Christian Bleiholder
This review focuses on the instrumental development and potential applications of Tandem-Trapped Ion Mobility Spectrometry/Mass Spectrometry (tTIMS/MS) for protein structure elucidation.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 03.05.2022


Biorecognition Antifouling Coatings in Complex Biological Fluids: A Review of Functionalization Aspects

Analyst, 2022, Accepted Manuscript
DOI: 10.1039/D2AN00436D, Critical Review
Ivana Víšová, Milan Houska, Hana Vaisocherová-Lísalová
Recent progress in biointerface research have highlighted the role of antifouling functionalizable coatings in the development of advanced biosensors for point-of-care bioanalytical and biomedical applications dealing with real-world complex samples....
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 03.05.2022


Probing low abundant DNA methylation by CRISPR-Cas12a-assisted cascade exponential amplification

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00170E, Paper
Liangliang Zhang, Xianxian Zhao, Xiaolin Hu, Yi Zhang, Ruining Liu, Hai Peng, Youhao Chen, Hong Zhang, Yang Luo
We propose an easy-to-operate CRISPR/Cas system Assisted Methylation (CAM) approach for the sensitive detection of DNA methylation through the integration of rolling circle amplification and CRISPR/Cas12a-assisted cascade amplification.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 03.05.2022


An ultrasensitive luteolin electrochemical sensor based on a glass carbon electrode modified using multi-walled carbon nanotube-supported hollow cobalt sulfide (CoSx) polyhedron/graphene quantum dot composites

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00345G, Paper
Li Zhang, Pengcheng Zhao, Chenxi Wang, Yilin Wang, Yaqi Yang, Yixi Xie, Junjie Fei
Fabrication of an electrochemical luteolin sensor composed of multi-walled carbon nanotube-supported hollow cobalt sulfide (CoSx) polyhedrons/graphene quantum dots and its application in actual sample detection.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 03.05.2022


Ratiometric fluorescent probe: a sensitive and reliable reporter for the CRISPR/Cas12a-based biosensing platform

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00613H, Paper
Qiang Liu, Mei Liu, Yan Jin, Baoxin Li
Using a ratiometric probe as the reporter for the CRISPR-Cas12a based biosensing system, the change of two fluorescence intensities can be monitored, while the TaqMan probe appears only one signal.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 03.05.2022


Single-particle spectroelectrochemistry: electrochemical tuning of plasmonic properties via mercury amalgamation in mesoporous silica coated gold nanorods without structural deformation

Analyst, 2022, 147,2035-2039
DOI: 10.1039/D2AN00559J, Communication
Yola Yolanda Alizar, Ji Won Ha
This paper presented the possibility of the in situ tuning of the LSPR properties of AuNRs@mSiO2 by Hg deposition via electrochemical potential manipulations without the disturbance of the structural variations of AuNR cores.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 02.05.2022


The unique physical shading pattern of Rayleigh scattering for the generally improved detection of scattering particles

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00488G, Paper
Zhihui Li, Yan Meng, Hongyu Nie, Rongmeng Gu, Xiaokun Wang, Dan Xiao
A facile physical shading method, based on the Rayleigh scattering pattern, exhibited excellent performance detection because of its reduced background noise.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 30.04.2022


Mimetic peroxidase based on a gold amalgam for the colorimetric sensing of trace mercury(II) in water samples

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00560C, Paper
Jing Jiang, Xianwen Kan
A simple and effective AuNPs/H-rGO/CC colorimetric sensing interface was constructed for the sensitive, selective, and facile determination of Hg2+ in water samples.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 30.04.2022


Enzyme-triggered click chemistry combined with surface-enhanced Raman spectroscopy for the simple and sensitive detection of alkaline phosphatase activity from complex biological samples

Analyst, 2022, Advance Article
DOI: 10.1039/D1AN02159A, Paper
Fanghao Cao, Minmin Wang, Xuan Yi, Dan Sun
Schematic of the enzyme-triggered click chemistry combined with the SERS technique for ALP detection.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 29.04.2022


H2O2-activated independently bidirectional regulation for a sensitive and accurate electrochemiluminescence ratiometric analysis

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00601D, Paper
Xiang-Mei Liu, Yu-Ling Wang, Shu-Wei Ren, Jun-Tao Cao, Yan-Ming Liu
A novel ECL ratiometric sensor was developed based on H2O2 activated independently bidirectional regulation strategy.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 29.04.2022


Correction: Fast label-free recognition of NRBCs by deep-learning visual object detection and single-cell Raman spectroscopy

Analyst, 2022, 147,2280-2280
DOI: 10.1039/D2AN90030K, Correction
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Teng Fang, Pengbo Yuan, Chen Gong, Yueping Jiang, Yuezhou Yu, Wenhao Shang, Chan Tian, Anpei Ye
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 28.04.2022


A multicolor biosensor for alkaline phosphatase activity detection based on the peroxidase activity of copper nanoclusters and etching of gold nanorods

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00517D, Paper
Qin Luo, Yisheng Lin, Qihong Cai, Fang Luo, Cuiying Lin, Jian Wang, Bin Qiu, Zhenyu Lin
A multicolor biosensor for ALP activity has been developed based on the peroxidase activity of copper nanoclusters and etching of gold nanorods.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 28.04.2022


Construction of Ag nanowire@Au nanoparticle nano nests with densely stacked small gaps for actively trapping molecules to realize diversity SERS detection

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00527A, Paper
Tao Xie, Pan Li, Meihong Ge, Siyu Chen, Guangyao Huang, Junxiang Li, Meiting Gong, Shirui Weng, Liangbao Yang
The SERS detection method based nano nest model actively traps molecules by the capillary action to detect different kinds of molecules, such as pesticide residues, bioenergy substances, antibiotic residues and allergic reactions.
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Datum: 28.04.2022


A multifunctional colorimetric sensor array for bacterial identification and real-time bacterial elimination to prevent bacterial contamination

Analyst, 2022, 147,2247-2252
DOI: 10.1039/D2AN00445C, Paper
Minyang Zhao, Yong Yan, Hanqiong Guo, Yujie Zhang, Haotian Wu, Yuan Fang, Yaqing Liu
The constructed sensor array has simple operation and successfully integrates bacterial identification and inactivation.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 28.04.2022


A polypyrrole-mediated photothermal biosensor with a temperature and pressure dual readout for the detection of protein biomarkers

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00370H, Paper
Eunyeong Song, Yingzhou Tao, Haicong Shen, Chaoyong Yang, Tian Tian, Liu Yang, Zhi Zhu
A novel photothermal biosensor with a temperature and pressure dual readout was developed for CRP detection. The in situ synthesized polypyrrole exhibits photothermal effect under NIR light to increase temperature and pressure for portable readout.
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Datum: 27.04.2022


Separation, identification, and confirmation of cyclic and tadpole macromolecules via UPLC-MS/MS

Analyst, 2022, 147,2089-2096
DOI: 10.1039/D2AN00208F, Paper
Jason M. O'Neill, Jialin Mao, Farihah M. Haque, Fabienne Barroso-Bujans, Scott M. Grayson, Chrys Wesdemiotis
LC-MS/MS enables the separation and relative quantitation of cyclic and tadpole architectures of poly(glycidyl phenyl ether)s synthesized via ring-opening zwitterionic polymerization (ZREP).
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Datum: 27.04.2022


A magnet-actuated microfluidic array chip for high-throughput pretreatment and amplification and detection of multiple pathogens

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00430E, Paper
Mengfan Zhou, Huiying Su, Bangfeng Wang, Chao Wan, Wei Du, Peng Chen, Xiaojun Feng, Bi-Feng Liu
The outbreak of global infectious diseases has posed a significant threat to public health, requiring the rapid and accurate diagnosis of pathogens promptly for society to implement immediate control measures to prevent widespread pandemics.
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The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 27.04.2022


Highly catalysis amplification of MOFNd-loaded nanogold combined with specific aptamer SERS/RRS assay of trace glyphosate

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00549B, Paper
Jingjing Li, Jinling Shi, Aihui Liang, Zhiliang Jiang
A novel SERS/RRS di-mode quantitative analysis method for glyphosate was established by coupling this new Au@MOFNd catalytic indicator reaction with the aptamer reaction of GLY.
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Datum: 27.04.2022


A designer DNA tetrahedron-based molecular beacon for tumor-related microRNA fluorescence imaging in living cells

Analyst, 2022, 147,2231-2237
DOI: 10.1039/D2AN00418F, Paper
Shuainan Li, Chenguang Wang, Yi Xu, Wei Wang, Xiaoshuang Zhao, Qiuling Qian, Xianqiang Mi
A designer nanoprobe of tetrahedral DNA framework (TDF) combined with MB (termed TDFM nanoprobe) for the efficient fluorescence imaging of tumor-related miRNA-214 in living cells.
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Datum: 26.04.2022


Detection of heterocyclic amine (PhIP) by fluorescently labelled cucurbit[7]uril

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00495J, Paper
Lili Sun, Zejiang Wang, Juan Hou, Guozhen Fang, Jifeng Liu, Shuo Wang
A “host–guest” system for 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) detection was designed. This method might be the first quick measurement technique for HCA and may find wide application in food safety detection.
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Datum: 24.04.2022


Bypassed ion-selective electrodes – self-powered polarization for tailoring of sensor performance

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00458E, Paper
Anna Kisiel, Agata Michalska, Krzysztof Maksymiuk
The bypass circuit with zinc wire induces spontaneous charge flow: oxidation of zinc and reduction of the solid contact of K-ISE. This effect is helpful in the improvement of analytical parameters of K-ISE.
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Datum: 23.04.2022


Rapid identification of human muscle disease with fibre optic Raman spectroscopy

Analyst, 2022, Advance Article
DOI: 10.1039/D1AN01932E, Paper
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
James J. P. Alix, Maria Plesia, Gavin R. Lloyd, Alexander P. Dudgeon, Catherine A. Kendall, Channa Hewamadduma, Marios Hadjivassiliou, Christopher J. McDermott, Gráinne S. Gorman, Robert W. Taylor, Pamela J. Shaw, John C. C. Day
We demonstrate the use of fibre optic Raman spectroscopy for the rapid identification of muscle disorders.
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Datum: 21.04.2022


Recent advances in spheroid-based microfluidic models to mimic the tumour microenvironment

Analyst, 2022, 147,2023-2034
DOI: 10.1039/D2AN00172A, Minireview
Jooyoung Ro, Junyoung Kim, Yoon-Kyoung Cho
Microfluidic platforms with 3D tumour spheroid culture provide platforms to study the multi-cellular interactions and external stimuli in the complex tumour microenvironment.
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Datum: 21.04.2022


A sensitive fluorescence biosensor based on metal ion-mediated DNAzyme activity for amplified detection of acetylcholinesterase

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00414C, Paper
Xu-Hua Zhao, Xiao-Chun Dai, Ya-Nan Zhou, Han-Xiao Zhang, Xiao-Hua Cui, Xiang Zhai, Bao-Feng Yu, Zhi-Ling Song
In this paper, we developed an amplified fluorescence biosensor for acetylcholinesterase (AChE) activity detection by taking advantage of the mercury ion-mediated Mgzyme (Mg2+-dependent DNAzyme) activity.
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Datum: 21.04.2022


Naphthalene-functionalized resorcinarene as selective, fluorescent self-quenching sensor for kynurenic acid

Analyst, 2022, 147,2264-2271
DOI: 10.1039/D1AN02224E, Paper
Anna Karle, Kwaku Twum, Noorhan Sabbagh, Alise Haddad, S. Maryamdokht Taimoory, Małgorzata M. Szczęśniak, Evan Trivedi, John F. Trant, Ngong Kodiah Beyeh
Naphthalene-functionalized resorcinarene selectively binds kynurenic acid in the presence of excess tryptophan in aqueous media, highlighting the potential of functionalized resorcinarenes as sensory recognition elements for biomolecular analytes.
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Datum: 21.04.2022


Fluorescence imaging of intracellular telomerase activity for tumor cell identification by oligonucleotide-functionalized gold nanoparticles

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00525E, Paper
Shan Shan, Jiajia Li, Guangmei Han, Ruilong Zhang, Zhengjie Liu, Zhongping Zhang
An oligonucleotide-functionalized gold nanoparticle probe was developed and the high-efficiency detection of telomerase activity for cellular imaging toward the identification of tumors was realized.
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Datum: 21.04.2022


A scaffold of thermally activated delayed fluorescent polymer dots towards aqueous electrochemiluminescence and biosensing applications

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00352J, Paper
Yelin Luo, Bolin Zhao, Baohua Zhang, Yeying Lan, Lijuan Chen, Yuwei Zhang, Yu Bao, Li Niu
Thermally activated delayed fluorescent (TADF) polymer dots were prepared, which enables aqueous electrochemiluminescence of TADF polymer emitters and its biosensor application for the first time.
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Datum: 21.04.2022


A label-free and ultrasensitive electrochemical biosensor for oral cancer overexpressed 1 gene via exonuclease III-assisted target recycling and dual enzyme-assisted signal amplification strategies

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00367H, Paper
Dongyou Zhang, Yali Wang, Xiaoyu Jin, Qi Xiao, Shan Huang
A label-free and ultrasensitive electrochemical biosensor for ORAOV1 gene via exonuclease III-assisted target recycling and dual enzyme-assisted signal amplification strategies. The detection limit of ORAOV1 gene was as low as 0.019 fM.
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Datum: 21.04.2022


A novel hydrophilic hydrogel with a 3D network structure for the highly efficient enrichment of N-glycopeptides

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00516F, Paper
Haozhou Jin, Wenqing Gao, Rong Liu, Jiaqian Yang, Shun Zhang, Renlu Han, Jing Lin, Sijia Zhang, Jiancheng Yu, Keqi Tang
A novel super-hydrophilic hydrogel (ZIF-8/SAP) was first proposed and facilely fabricated to capture N-glycopeptides from complex biological samples with excellent selectivity and sensitivity.
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Datum: 21.04.2022


A dual-signal electrochemical immunosensor for the detection of HPV16 E6 oncoprotein based on PdBP dendritic ternary nanospheres and MBSi-Chi nanocomposites

Analyst, 2022, 147,2272-2279
DOI: 10.1039/D1AN02120F, Paper
Tao Wen, Chenchen Xia, Qiubo Yu, Yujie Yu, Siyuan Li, Chunli Zhou, Kexin Sun, Song Yue
A dual-signal electrochemical immunosensor was fabricated to detect HPV16 E6 oncoprotein for the first time, which meets the requirements for a quick and sensitive detection.
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Datum: 21.04.2022


In situ photoinitiated fabrication of phosphorylcholine-functionalized polyhedral oligomeric silsesquioxane hybrid monolithic column for mixed-mode capillary electrochromatography

Analyst, 2022, 147,2253-2263
DOI: 10.1039/D2AN00195K, Paper
Xiaoyun Lei, Bingyu Zhang, Yi Zhang, Ting Huang, Fengxiang Tang, Xiaoping Wu
A phosphorylcholine-functionalized POSS hybrid monolithic column was synthesized via UV curing. It exhibits hydrophilic interaction and weak cation exchange chromatography retention mechanism for the separation of typical polar and charged compounds.
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Datum: 20.04.2022


Dual-channel detection of viscosity and pH with a near-infrared fluorescent probe for cancer visualization

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00547F, Paper
Xiyuan Zhang, Fangjun Huo, Yongbin Zhang, Yongkang Yue, Caixia Yin
Compared to ordinary cells, tumor cells have a unique microenvironment, characterized by high viscosity, low pH, high reactive oxygen species level and the overexpression of certain proteases.
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Datum: 20.04.2022


2D and 3D maximum-quantum NMR and diffusion spectroscopy for the characterization of enzymatic reaction mixtures

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00200K, Paper
Elena Piersanti, Claudio Righetti, David Ribeaucourt, A. Jalila Simaan, Yasmina Mekmouche, Mickael Lafond, Jean-Guy Berrin, Thierry Tron, Mehdi Yemloul
Using MaxQ-NMR, we characterized enzymatic reaction mixtures containing several compounds (substrate, final product, and various intermediates). This approach enables, in a first analytical step, the counting of the molecules present in the samples.
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Datum: 19.04.2022


Aptazyme-induced cascade amplification integrated with a volumetric bar-chart chip for highly sensitive detection of aflatoxin B1 and adenosine triphosphate

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00650B, Paper
Yuanyue Han, Xinli Liu, Qiao Zhao, Yanfeng Gao, Dongtao Zhou, Wenxiu Long, Yuzhen Wang, Yujun Song
A triple-channel volumetric bar-chart chip based on aptazyme-induced cascade signal amplification empowers visual readout of aflatoxin B1 and adenosine triphosphate concentration.
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Datum: 19.04.2022


The protective effect of biomineralized BSA-Mn3O4 nanoparticles on HUVECs investigated by atomic force microscopy

Analyst, 2022, 147,2097-2105
DOI: 10.1039/D2AN00483F, Paper
Xinyue Guo, Weiqi Zhou, Yanxue Guan, Juan Qin, Bailin Zhang, Miaomiao Zhang, Jilin Tang
BSA-Mn3O4 nanoparticles were successfully synthesized by one-step biomineralization method, the mechanism of antioxidant activity of BSA-Mn3O4 nanoparticles in HUVECs was investigated from the perspective of biomechanics.
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Datum: 19.04.2022


Rapid separation of cannabinoid isomer sets using differential mobility spectrometry and mass spectrometry

Analyst, 2022, 147,2198-2206
DOI: 10.1039/D1AN02327F, Paper
Nour Mashmoushi, J. Larry Campbell, Robert di Lorenzo, W. Scott Hopkins
With legalization and decriminalization of cannabis in many parts of the world comes the need for rapid separation and quantitation of the psychoactive ingredients.
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Datum: 19.04.2022


A controllable staining colorimetric method based on carboxylated cellulose membranes for early-warning and semi-quantitative detection of aflatoxins in water

Analyst, 2022, Advance Article
DOI: 10.1039/D1AN02355A, Paper
Heng Zhang, Wenhui Zhong, Yang Yang, Genyan Liu, Xiaogang Luo
A controllable staining colorimetric method was proposed for antibody-free detection of AFs by exploiting controllable electrostatic-staining of CCMs with Hg2+-capped AuNPs.
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Datum: 18.04.2022


Triblock probe-polyA-probe electrochemical interfacial engineering for the sensitive analysis of RNAi plants

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00366J, Paper
Yu Zheng, Lele Wang, Li Xu, Yan Li, Xue Yang, Zhenzhou Yang, Lanying Li, Min Ding, Shuzhen Ren, Feiyan Gong, Jinxue Chang, Chengming Cao, Yanli Wen, Liang Li, Gang Liu
RNA interference (RNAi) is under fast development in agriculture and brings new challenge for GMO analysis. We developed a electrochemical biosensor for the analysis of GM maize samples based on a polyA-DNA capturing probe. Ultrasensitive detection of 10 fM RNA was realized.
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Datum: 15.04.2022


Rational design of a facile camphor-based fluorescence turn-on probe for real-time tracking of hypochlorous acid in vivo and in vitro

Analyst, 2022, 147,2080-2088
DOI: 10.1039/D2AN00321J, Paper
Zhonglong Wang, Yan Zhang, Yueyin Liang, Mingxin Li, Zhiyuan Meng, Shuai Gong, Yiqin Yang, Xu Xu, Shifa Wang
A novel camphor-based fluorescence turn-on probe with high selectivity and sensitivity was developed for HClO detection, and it was successfully employed for real-time imaging of exogenous and endogenous HClO in living cells as well as in living zebrafish.
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Datum: 15.04.2022


Raman spectrum matching with contrastive representation learning

Analyst, 2022, 147,2238-2246
DOI: 10.1039/D2AN00403H, Paper
Bo Li, Mikkel N. Schmidt, Tommy S. Alstrøm
An effective contrastive representation learning method for spectra identification with a frequentist guarantee of including the correct class prediction on two Raman datasets (Mineral and Organic) and one SERS dataset (Bacteria).
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Datum: 15.04.2022


Electrochemiluminescent sensor based on an aggregation-induced emission probe for bioanalytical detection

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00349J, Tutorial Review
Xiaoyi Lv, Yanping Li, Bo Cui, Yishan Fang, Lishi Wang
In recent years, with the rapid development of electrochemiluminescence (ECL) sensors, more luminophores have been designed to achieve high-throughput and reliable analysis.
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Datum: 14.04.2022


Multiple stem-loop primers induced cascaded loop-mediated isothermal amplification for direct recognition and specific detection of circular RNAs

Analyst, 2022, 147,2124-2129
DOI: 10.1039/D2AN00261B, Paper
Xin Liu, Pengbo Zhang, Kejian Gao, Xiaoyu Wang, Zhengping Li
Through specific recognition of circRNA's unique junction sequence, a multiple stem-loop primers induced cascaded loop-mediated isothermal amplification method is designed for sensitive and specific quantification of sequence-specific circRNAs.
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Datum: 14.04.2022


Sensitive detection of fusion transcripts with padlock probe-based continuous cascade amplification (P-CCA)

Analyst, 2022, 147,2207-2214
DOI: 10.1039/D2AN00341D, Paper
Yutong Chen, Fengxia Su, Yongqiang Cheng, Xiaofei He, Zhengping Li
A padlock probe-based continuous cascade amplification (P-CCA) is proposed for assaying fusion transcripts with high sensitivity and specificity.
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Datum: 12.04.2022


Hyphenated structural identification of additives in transmission fluids

Analyst, 2022, 147,2068-2073
DOI: 10.1039/D2AN00323F, Paper
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
F. H. M. van Zelst, J. Romanuka, A. P. M. Kentgens
A novel hyphenated analytical method to unravel complex mixtures, SFC-1H NMR/MS, is introduced. It is applied for the structural analysis of additives in transmission fluids which can be used to prolong the lifetime of lubricants.
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Datum: 11.04.2022


Sulfur atom modification on thymine improves the specificity and sensitivity of DNA polymerization and detection

Analyst, 2022, 147,2164-2169
DOI: 10.1039/D1AN02017J, Paper
Yang Li, Wen Sun, Danyan Luo, Zhaoyi Yang, Wei He, Zhen Huang
The incorporation of STTP can significantly reduce the non-specific amplification products in DNA polymerase reaction.
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Datum: 11.04.2022


Ultra-bright carbon quantum dots for rapid cell staining

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00325B, Paper
Tongtong Zhu, Lei Cao, Zhenqiao Zhou, Hanzhou Guo, Mingfeng Ge, Wen-Fei Dong, Li Li
A schematic illustration of the synthesis of G-CDs and cell imaging under one-photon and two-photon conditions.
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Datum: 11.04.2022


The application of physics-informed neural networks to hydrodynamic voltammetry

Analyst, 2022, 147,1881-1891
DOI: 10.1039/D2AN00456A, Paper
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Haotian Chen, Enno Kätelhön, Richard G. Compton
Electrochemical problems are widely studied in flowing systems since the latter offer improved sensitivity notably for electro-analysis and the possibility of steady-state measurements for fundamental studies even with macro-electrodes.
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Datum: 09.04.2022


Single-cell droplet microfluidics for biomedical applications

Analyst, 2022, Advance Article
DOI: 10.1039/D1AN02321G, Critical Review
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Dan Liu, Meilin Sun, Jinwei Zhang, Rui Hu, Wenzhu Fu, Tingting Xuanyuan, Wenming Liu
This review focuses on the recent advances in the fundamentals of single-cell droplet microfluidics and its applications in biomedicine, providing insights into design and establishment of single-cell microsystems and their further performance.
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Datum: 09.04.2022


Ultrasensitive multiwall carbon nanotube-mesoporous MCM-41 hybrid-based platform for the electrochemical detection of ascorbic acid

Analyst, 2022, 147,2130-2140
DOI: 10.1039/D2AN00473A, Paper
Virginia M. Vaschetti, Benjamín N. Viada, Alejandro Tamborelli, Griselda A. Eimer, Gustavo A. Rivas, Pablo R. Dalmasso
An ultrasensitive multiwall carbon nanotube-MCM-41 hybrid-based ascorbic acid sensor for electro-detection in real samples is proposed. The MWCNT–MCM-41 hybrid preparation via dispersion was optimized through an experimental design based on CCD/RSM.
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Datum: 08.04.2022


A genosensor for detecting single-point mutations in dendron chips after blocked recombinase polymerase amplification

Analyst, 2022, 147,2180-2188
DOI: 10.1039/D2AN00160H, Paper
Sara Martorell, Ángel Maquieira, Luis A. Tortajada-Genaro
Dendron–probe conjugates were effectively immobilized on chip surfaces, improving assay sensitivity and simplifying coupling reactions. Combined with an isothermal amplification, the array method accurately detects single-base changes.
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Datum: 07.04.2022


The simultaneous quantitative detection of multiple hormones based on PS-MS: affinity capture by a single antibody

Analyst, 2022, 147,1853-1858
DOI: 10.1039/D2AN00029F, Paper
Tianhao Wu, Mingying Ma, Gongwei Sun, Sichun Zhang, Xinrong Zhang
Here, we utilized single antibody to capture and separate multiple hormones from samples to avoid LC procedures and MS/MS detection to realize simultaneously qualitative and quantitative analysis of multiple molecules in a single run.
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Datum: 07.04.2022


A sensing system constructed by combining a structure-switchable molecular beacon with nicking-enhanced rolling circle amplification for highly sensitive miRNA detection

Analyst, 2022, 147,1937-1943
DOI: 10.1039/D1AN02218K, Paper
Shujuan Sun, Wenqing Wang, Xuemei Hu, Cheng Zheng, Qi Xiang, Qingguo Yang, Jing Zhang, Zhi-Fa Shen, Zai-Sheng Wu
A novel amplification assay strategy is developed for the highly sensitive detection of miRNA-21 based on a combination of a structure-switchable molecular beacon with nicking-enhanced rolling circle amplification.
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Datum: 07.04.2022


Profiling of branched-chain fatty acids via nitroxide radical-directed dissociation integrated on an LC-MS/MS workflow

Analyst, 2022, 147,2115-2123
DOI: 10.1039/D2AN00266C, Paper
Ruijun Jian, Xue Zhao, Qiaohong Lin, Yu Xia
By coupling O-benzylhydroxylamine derivatization and tandem mass spectrometry, nitroxide radical-induced dissociation can be initiated via collisional activation which enables the analysis of methyl branching(s) in fatty acids.
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Datum: 07.04.2022


An improved dual-channel capacitively coupled contactless conductivity detector with high detection performance

Analyst, 2022, 147,2106-2114
DOI: 10.1039/D2AN00330A, Paper
Hongyu Nie, Zhihui Li, Xiaokun Wang, Rongmeng Gu, Hongyan Yuan, Yong Guo, Dan Xiao
This work proposes a differential multi-input capacitively coupled contactless conductivity detector (DFMIC4D) with better detection performance than other existing set-ups.
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Datum: 06.04.2022


Diagnostic value of serum sphingolipids in patients with colorectal cancer

Analyst, 2022, 147,2189-2197
DOI: 10.1039/D1AN02239C, Paper
Ziyue Pan, Zuojian Hu, Li Guan, Lei Zhang, Xia Gao, Lujie Yang, Tianqi Gong, Yanling Hu, Yanping Zhao, Hongxiu Yu
We compared serum sphingolipids in healthy individuals, and polyp and colorectal cancer patients, and found that serum sphingolipid profiles shift during the development of cancer.
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Datum: 06.04.2022


Enhancing scanning electrochemical microscopy's potential to probe dynamic co-culture systems via hyperspectral assisted-imaging

Analyst, 2022, Advance Article
DOI: 10.1039/D2AN00319H, Paper
Sondrica Goines, Mingchu Deng, Matthew W. Glasscott, Justin W. C. Leung, Jeffrey E. Dick
Overcoming challenges associated with biological imaging by correlating hyperspectral imaging and scanning electrochemical microscopy; this powerful combination provides unambiguous determination of cell boundaries for studying cellular dynamics.
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Datum: 05.04.2022


An ultrasensitive electrochemical sensing platform based on silver nanoparticle-anchored 3D reduced graphene oxide for rifampicin detection

Analyst, 2022, 147,2156-2163
DOI: 10.1039/D2AN00452F, Paper
Qing Zhang, Shangshang Ma, Xin Zhuo, Cong Wang, Hongyan Wang, Yuying Xing, Qingyuan Xue, Keying Zhang
An accurate and reliable electrochemical sensor based on Ag NPs/3D rGO composites for ultrasensitive determination of rifampicin (RIF) is proposed and shows great potential application in clinical diagnosis, pharmaceuticals and food-related fields.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 05.04.2022


Hairpin-functionalized DNA tetrahedra for miRNA imaging in living cells via self-assembly to form dendrimers

Analyst, 2022, 147,2074-2079
DOI: 10.1039/D2AN00080F, Paper
Wenjing Zhao, Yao Jiang, Huimin Zhou, Shusheng Zhang
A DNA tetrahedron-based intramolecular catalytic hairpin self-assembly platform that uses fluorescence signals to image miRNAs in live cells for accurate tumor cell identification.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 05.04.2022


Preparation of a disposable electrochemiluminescence sensor chip based on an MXene-loaded ruthenium luminescent agent and its application in the detection of carcinoembryonic antigens

Analyst, 2022, 147,1986-1994
DOI: 10.1039/D2AN00450J, Paper
Weiwei Luo, Zhuoxin Ye, Pinyi Ma, Qiong Wu, Daqian Song
We developed a novel type of disposable ECL sensor chip for CEA detection in serum samples of healthy humans and cancer patients. The disposable ECL sensor chip has many advantages including convenience, rapid detection, low cost, and easy mass production.
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Datum: 05.04.2022


A sensitive and simple competitive nanozyme-linked apta-sorbent assay for the dual-mode detection of ochratoxin A

Analyst, 2022, 147,2215-2222
DOI: 10.1039/D1AN02335G, Paper
Min Li, Hao Wang, Xiaodi Yu, Xindi Jia, Chao Zhu, Jiahui Liu, Fan Zhang, Zilei Chen, Mengmeng Yan, Qinzheng Yang
Pd–Pt NRs bound with capture probes catalyzed the conversion of colorless TMB to blue TMB2+. The TMB not only had a distinguishable change in the color but also had a strong SERS signal.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 02.04.2022


DNA walker-amplified signal-on electrochemical aptasensors for prostate-specific antigen coupling with two hairpin DNA probe-based hybridization reaction

Analyst, 2022, 147,1923-1930
DOI: 10.1039/D2AN00327A, Paper
Yuyu Zheng, Jinpeng Wang, Genwang Chen, Meie Wang, Tebin Chen, Qiaohong Ke, Yajun Huang, Fan Cai, Rongfu Huang, Chunmei Fan
An electrochemical aptasensing platform was designed for the voltammetric detection of prostate-specific antigen without any washing and separation steps.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 02.04.2022


Nanomaterial-assisted thread-based isotachophoresis with on-thread solute trapping

Analyst, 2022, 147,1944-1951
DOI: 10.1039/D2AN00287F, Paper
Liang Chen, Alireza Ghiasvand, Estrella Sanz Rodriguez, Peter C. Innis, Brett Paull
This research describes a nanomaterial-assisted TB-ITP setup for the clean-up, preconcentration, and trapping of alkaloids in biological fluids, followed by their on-thread DESI-MS determination.
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Datum: 01.04.2022


Magnetic solid-phase extraction of pyrethroid and neonicotinoid insecticides separately in environmental water samples based on alkaline or acidic group-functionalized mesoporous silica

Analyst, 2022, 147,1995-2007
DOI: 10.1039/D2AN00088A, Paper
Rui Han, Fei Wang, Chuanfeng Zhao, Meixing Zhang, Shihai Cui, Jing Yang
In this work, amino- or carboxyl-functionalized magnetic KIT-6 have been synthesized separately. The two nanocomposites were successfully used to enrich pyrethroids and neonicotinoids insecticides from environmental water samples, respectively.
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Datum: 01.04.2022


A novel and portable electrochemical sensor for 5-hydroxymethylfurfural detection using silver microdendrite electrodeposited paper-based electrode

Analyst, 2022, 147,2170-2179
DOI: 10.1039/D2AN00346E, Paper
Jantima Upan, Jamras Lerdsri, Jittrapun Soongsong, Pijika Mool-am-kha, Tharinee Sridara, Preeyaporn Reanpang, Jaroon Jakmunee
A lab-made screen-printed carbon electrode was fabricated on poster paper and modified with silver microdendrites for the determination of 5-hydroxymethylfurfural in honey.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 01.04.2022


A primer extension activating 3D DNAzyme walker for in situ imaging and sensitive detection of telomerase activity

Analyst, 2022, 147,1968-1975
DOI: 10.1039/D2AN00142J, Paper
Xiaoting Liu, Liyan Zhang, Ling Lu, Wei Jiang, Nan Zhang
A primer extension activating 3D DNAzyme walker has been developed for in situ imaging and sensitive detection of telomerase activity.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 31.03.2022


CdSe/ZnS quantum dot-encoded maleic anhydride-grafted PLA microspheres prepared through membrane emulsification for multiplexed immunoassays of tumor markers

Analyst, 2022, 147,1873-1880
DOI: 10.1039/D2AN00350C, Paper
Wan-Sheng Tang, Bo Zhang, Lai-Di Xu, Ning Bao, Qing Zhang, Shou-Nian Ding
Liquid suspension biochips based on quantum dots (QDs) encoded microspheres have been widely used in the immunodetection of tumor markers.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 31.03.2022


A bright chemiluminescence conjugated polymer–mesoporous silica nanoprobe for imaging of colonic tumors in vivo

Analyst, 2022, 147,2060-2067
DOI: 10.1039/D2AN00294A, Paper
Yukun Li, Beibei Zhu, Wanying Han, Wei Tang, Xinrui Duan
A chemiluminescence (CL) conjugated polymer–mesoporous silica nanoprobe with significant improvement of CL quantum yield obtained from direct oxidation of a conjugated polymer and its application for in vivo imaging of colonic tumors.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 31.03.2022


A simple fluorescent strategy for liver capillary labeling with carbon quantum dot-lectin nanoprobe

Analyst, 2022, 147,1952-1960
DOI: 10.1039/D1AN02364K, Paper
Chang-Zhi An, Chao-Qing Li, Lai-Bo Song, Yan-Fei He, Wei Chen, Bo Liu, Yuan-Di Zhao
Based on lycopersicon esculentum lectin that can target vascular endothelial cells and carbon quantum dots, we designed a carbon-based probe for the fluorescence labeling and imaging of hepatic blood vessels of liver tissue sections.
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Datum: 31.03.2022


Effects of the interaction of gunshot residue plume and cotton fabrics—an empirical study towards extensive assessment of close-range shooting distance

Analyst, 2022, 147,2141-2155
DOI: 10.1039/D1AN02001C, Paper
Zuzanna Brożek-Mucha, Jolanta Wąs-Gubała
This study is focused on the distribution of gunshot residue as well as changes in the textiles to support forensic investigations of suicides and homicides committed by means of a firearm.
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Datum: 31.03.2022


Establishing a quantitative fluorescence assay for the rapid detection of kynurenine in urine

Analyst, 2022, 147,1931-1936
DOI: 10.1039/D2AN00107A, Paper
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kamlesh Patel, Marcos Fernandez-Villamarin, Craig Ward, Janet M. Lord, Peter Tino, Paula M. Mendes
A fluorescence-based assay for the detection of kynurenine in urine for low-cost and high-throughput analysis in clinical laboratory settings.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 30.03.2022


Tetrahedral DNA-directed core-satellite assembly as SERS sensor for mercury ions at the single-particle level

Analyst, 2022, 147,1866-1872
DOI: 10.1039/D2AN00402J, Paper
Ning Feng, Jingjing Shen, Chang Li, Qianqian Zhao, Essy Kouadio Fodjo, Lei Zhang, Shufen Chen, Quli Fan, Lianhui Wang
We have designed a single-particle detection assay for quantifying Hg2+ by DFM-correlated Raman spectroscopy. A tetrahedral DNA-directed core-satellite nanostructure is used as the SERS probe.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 30.03.2022


Ultrasensitive detection of tumor-derived small extracellular vesicles based on nonlinear hybridization chain reaction fluorescence signal amplification and immunomagnetic separation

Analyst, 2022, 147,1859-1865
DOI: 10.1039/D2AN00242F, Paper
Qianqian Kong, Shasha Cheng, Xinyu Hu, Jia You, Cuiling Zhang, Yuezhong Xian
An ultrasensitive nonlinear hybridization chain reaction signal amplification fluorescence assay for the detection of small extracellular vesicles.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 30.03.2022


Simple add-on devices to enhance the efficacy of conventional surface immunoassays implemented on standard labware

Analyst, 2022, 147,2040-2047
DOI: 10.1039/D2AN00214K, Paper
Iago Pereiro, Anna Fomitcheva Kartchenko, Robert D. Lovchik, Govind V. Kaigala
We propose microfluidic add-ons easily placed on standard assay labware such as microwells and slides to enhance the kinetics of immunoassays. The devices are compatible with mass production, well-established assay protocols and automated platforms.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 17.03.2022


Isomeric separation of permethylated glycans by extra-long reversed-phase liquid chromatography (RPLC)-MS/MS

Analyst, 2022, 147,2048-2059
DOI: 10.1039/D2AN00010E, Paper
Junyao Wang, Xue Dong, Aiying Yu, Yifan Huang, Wenjing Peng, Yehia Mechref
Separation of glycans with sialic acid linkage isomers and positional fucosylated isomers derived from model glycoproteins, human serum and cancer cell lines using LC-MS/MS with a 500 mm reversed-phase C18 column.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 17.03.2022


DNA tile self-assembly driven by antibody-mediated four-way branch migration

Analyst, 2022, 147,2223-2230
DOI: 10.1039/D1AN02273C, Paper
Xingdi Cui, Yuan Liu, Qiang Zhang
The antibody-mediated four-way branch migration mechanism provides a novel idea for realizing the assembly of nanostructures, simply by attaching structures such as tiles, proteins, quantum dots, etc. to the ends of the four-way branches.
The content of this RSS Feed (c) The Royal Society of Chemistry

Datum: 14.02.2022


 


Category: Current Chemistry Research

Last update: 28.03.2018.






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