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Protecting Groups

Protective groups used in organic chemistry and synthesis.




In chemistry a protecting group - or: protective group - is used in synthesis to temporarily mask the characteristic chemistry of a functional group because it interferes with another reaction.

Online available information resources about chemical protecting groups.



Content, Topics


Current Articles
Lecture Notes, Tutorials
Special Information
Data and Databases
Dissertations



Current Articles


Protecting Groups
Amino; Carbonyl; Carboxyl; Hydroxyl (1,2-; 1,3-Diols) - Stability. Organic Chemistry Portal

Protecting Groups
Some protective groups udes in organic synthesis - Format: PDF

Protecting Groups
Review: protecting group strategies in organic synthesis. Royal Society of Chemistry, UK



Lecture Notes, Tutorials


Protecting Groups
... for organic synthesis - Format: PDF

Protecting Groups
A valuable addition to the synthetic chemist's bookshelf. The focus is on a relatively small number of commonly used protecting groups, on deprotecting conditions, and on the extensive use of schemes to aid visual retrieval of information.. Thieme, eBook

Protective Groups in Organic Chemistry
Supplemental slides - Format: PDF

Silicon
Silicon-Based Protecting Groups - Format: PDF



Special Information


Acetals as Protecting Group
An overview with example reactions

Alcohol Protecting Groups
An overview with example reactions

Alcohols
Protecting Groups for Alcohols

Alcohols and phenols
Protection of alcohols and phenols with methoxymethyl acetate

Amine Protecting Groups
Protective groups for amines

Amino Acid-Protecting Groups
... listed by amino acid - Format: PDF

Amino acids
Synthetic protecting groups for amino acids

Boc-Protected Amino Groups
tert-Butyl carbamates. Organic Chemistry Portal, Switzerland

Carbohydrates
Protecting groups in carbohydrate chemistry - Format: PDF

Carbonyl Protecting Groups
Protective groups for the carbonyl group

Diol Protecting Groups
An overview with example reactions

Monohalo Ethers in Protection Chemistry
Applications and mechanisms

Peptide Synthesis
Protecting groups used in peptide synthesis

Peptide Synthesis
Protecting groups used in peptide synthesis - Format: PDF

Protecting Groups
... in organic synthesis, for oxygen-based functionality etc - Format: PDF

Silicon-Based Protection of the Hydroxyl Group
An overview with example reactions - Format: PDF

Silyl Protective Groups
Effective protective groups for alcohols



Data and Databases


Protecting groups
SynArchive : A total synthesis database

Protecting Groups Chemical Database
MSAccess database. Description of circa 170 protecting groups, their formation, removal and use in organic synthesis



Dissertations


Highly Efficient Photolabile Protecting Groups
with Intramolecular Energy Transfer. University of Konstanz, Germany, 2006

 


Last update: 09.11.2018.






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