Organic Letters

Current research reports and chronological list of recent articles.


The international scientific journal Organic Letters serves as the international forum for the communication of important research in all branches of the theory and practice of: organic chemistry (including organometallic and materials chemistry); physical and theoretical organic chemistry; natural products isolation and synthesis; new synthetic methodology; bioorganic and medicinal chemistry.

The publisher is the American Chemical Society, ACS. The copyright and publishing rights of specialized products listed below are in this publishing house. This is also responsible for the content shown.

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Additional research articles see Current Chemistry Research Articles. Magazines with similar content (organic chemistry):

 - Beilstein Journal of Organic Chemistry.

 - European Journal of Organic Chemistry.

 - Journal of Organic Chemistry.

 - Journal of Physical Organic Chemistry.

 - Organic Process Research and Development.

 - Russian Journal of Organic Chemistry.

 - Synlett.



Organic Letters - Abstracts



Rh-Catalyzed Conjugate Addition of Arylzinc Chlorides to Thiochromones: A Highly Enantioselective Pathway for Accessing Chiral Thioflavanones

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Organic Letters
DOI: 10.1021/acs.orglett.6b02453

Datum: 26.09.2016


Alkylation of Nonacidic C(sp3)–H Bonds by Photoinduced Catalytic Michael-Type Radical Addition

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Organic Letters
DOI: 10.1021/acs.orglett.6b02391

Datum: 26.09.2016


Room Temperature Catalyst System for the Hydroarylation of Olefins

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Organic Letters
DOI: 10.1021/acs.orglett.6b02492

Datum: 26.09.2016


Synthesis of Trifluoromethyl-allenes by Gold-Catalyzed Rearrangement of Propargyl Benzyl Ethers

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Organic Letters
DOI: 10.1021/acs.orglett.6b02636

Datum: 26.09.2016


1,4-Addition Ugi Reaction Using Cyclic α,β-Unsaturated Ketone as Substrate

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Organic Letters
DOI: 10.1021/acs.orglett.6b02493

Datum: 23.09.2016


Synthesis of Enantioenriched 2-Alkyl Piperidine Derivatives through Asymmetric Reduction of Pyridinium Salts

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Organic Letters
DOI: 10.1021/acs.orglett.6b02401

Datum: 23.09.2016


Expanding the Scope of the Gold(I)-Catalyzed Rautenstrauch Rearrangement: Protic Additives

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Organic Letters
DOI: 10.1021/acs.orglett.6b02505

Datum: 23.09.2016


Strategies for the Total Synthesis of Diverse Bromo-Chamigrenes

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Organic Letters
DOI: 10.1021/acs.orglett.6b02478

Datum: 23.09.2016


Gated Photochromic System of Diarylethene with a Photon-Working Key

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Organic Letters
DOI: 10.1021/acs.orglett.6b02494

Datum: 23.09.2016


Photocatalytic Oxidation of Lignin Model Systems by Merging Visible-Light Photoredox and Palladium Catalysis

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Organic Letters
DOI: 10.1021/acs.orglett.6b02651

Datum: 23.09.2016


Tandem O–H Insertion/[1,3]-Alkyl Shift of Rhodium Azavinyl Carbenoids with Benzylic Alcohols: A Route To Convert C–OH Bonds into C–C Bonds

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Organic Letters
DOI: 10.1021/acs.orglett.6b02459

Datum: 23.09.2016


Stereospecific Synthesis of Tetrahydronaphtho[2,3-b]furans Enabled by a Nickel-Promoted Tandem Reductive Cyclization

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Organic Letters
DOI: 10.1021/acs.orglett.6b02665

Datum: 23.09.2016


Catalytically Generated Allyl Cu(I) Intermediate via Cyclopropene Ring-Opening Coupling en Route to Allylphosphonates

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Organic Letters
DOI: 10.1021/acs.orglett.6b02307

Datum: 22.09.2016


Tetra- and Octapyrroles Synthesized from Confusion and Fusion Approaches

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Organic Letters
DOI: 10.1021/acs.orglett.6b02495

Datum: 22.09.2016


Synthesis of Nitrogen Heterocycles via Photochemical Ring Opening of Pyridazine N-Oxides

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Organic Letters
DOI: 10.1021/acs.orglett.6b02562

Datum: 22.09.2016


Iron-Catalyzed [2 + 2 + 2] Cycloaddition Reactions of Diynes with Oxyphosphaethynes To Construct 2-Phosphaphenol Derivatives

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Organic Letters
DOI: 10.1021/acs.orglett.6b02462

Datum: 22.09.2016


Exploring the Scope of Asymmetric Synthesis of β-Hydroxy-γ-lactams via Noyori-type Reductions

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Organic Letters
DOI: 10.1021/acs.orglett.6b02416

Datum: 22.09.2016


Metal/Benzoyl Peroxide (BPO)-Controlled Chemoselective Cycloisomerization of (o-Alkynyl)phenyl Enaminones: Synthesis of α-Naphthylamines and Indeno[1,2-c]pyrrolones

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Organic Letters
DOI: 10.1021/acs.orglett.6b02615

Datum: 21.09.2016


AlCl3-Catalyzed Annulations of Ynamides Involving a Torquoselective Process for the Simultaneous Control of Central and Axial Chirality

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Organic Letters
DOI: 10.1021/acs.orglett.6b02480

Datum: 21.09.2016


Synthesis of Enantioenriched Pyrrolidines via Gold-Catalyzed Tandem Cycloisomerization/Hydrogenation of Chiral Homopropargyl Sulfonamides

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Organic Letters
DOI: 10.1021/acs.orglett.6b02736

Datum: 21.09.2016


Catalytic Multisite-Selective Acetoxylation Reactions at sp2 vs sp3 C–H Bonds in Cyclic Olefins

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Organic Letters
DOI: 10.1021/acs.orglett.6b02458

Datum: 21.09.2016


Access to a Structurally Complex Compound Collection via Ring Distortion of the Alkaloid Sinomenine

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Organic Letters
DOI: 10.1021/acs.orglett.6b02333

Datum: 21.09.2016


Cyclo[4]carbazole, an Iodide Anion Macrocyclic Receptor

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Organic Letters
DOI: 10.1021/acs.orglett.6b02500

Datum: 21.09.2016


Michael Addition–Lactonization of Arylacetyl Phosphonate to β,γ-Unsaturated α-Keto Esters for the Synthesis of Chiral syn-3,4-Dihydropyranones and 5,6-Dihydropyranones

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Organic Letters
DOI: 10.1021/acs.orglett.6b02558

Datum: 21.09.2016


Nazarov Cyclization/Internal Redox Cyclization Sequence for the Synthesis of N-Heterocyclic Bridged Ring Systems

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Organic Letters
DOI: 10.1021/acs.orglett.6b02369

Datum: 21.09.2016


Divergent Synthesis of Dihydroxanthene-Hemicyanine Fused Near-Infrared Fluorophores through the Late-Stage Amination of a Bifunctional Precursor

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Organic Letters
DOI: 10.1021/acs.orglett.6b02564

Datum: 20.09.2016


Synthesis of Spiromamakone A Benzo Analogues via Double Oxa-Michael Addition of 1,8-Dihydroxynaphthalene

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Organic Letters
DOI: 10.1021/acs.orglett.6b02328

Datum: 20.09.2016


Rh(III)-Catalyzed Carbocyclization of 3-(Indolin-1-yl)-3-oxopropanenitriles with Alkynes and Alkenes through C–H Activation

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Organic Letters
DOI: 10.1021/acs.orglett.6b02521

Datum: 20.09.2016


Diastereoselective Cobalt-Mediated Cross-Couplings of Cycloalkyl Iodides with Alkynyl or (Hetero)Aryl Grignard Reagents

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Organic Letters
DOI: 10.1021/acs.orglett.6b02119

Datum: 20.09.2016


Acid-Catalyzed Activation of Peroxyketals: Tunable Radical Initiation at Ambient Temperature and Below

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Organic Letters
DOI: 10.1021/acs.orglett.6b02419

Datum: 20.09.2016


Synthesis of Tertiary Enamides by Ag2CO3-Promoted Pd-Catalyzed Alkenylation of Acyclic Secondary Amides

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Organic Letters
DOI: 10.1021/acs.orglett.6b02305

Datum: 20.09.2016


Synthesis of α-Halo-γ-hydroxyenamides by Titanium Tetrahalide Mediated Addition of Aldehydes or Ketones to Ynamides

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Organic Letters
DOI: 10.1021/acs.orglett.6b02526

Datum: 20.09.2016


Total Synthesis of (−)-Neocosmosin A via Intramolecular Diels–Alder Reaction of 2-Pyrone

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Organic Letters
DOI: 10.1021/acs.orglett.6b02575

Datum: 20.09.2016


Bu4NI-Catalyzed Cross-Coupling between Sulfonyl Hydrazides and Diazo Compounds To Construct β-Carbonyl Sulfones Using Molecular Oxygen

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Organic Letters
DOI: 10.1021/acs.orglett.6b02532

Datum: 20.09.2016


Iridium-Catalyzed Direct ortho-C–H Amidation of Benzaldehydes through N-Sulfonyl Imines as Mask

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Organic Letters
DOI: 10.1021/acs.orglett.6b02406

Datum: 20.09.2016


Copper-Catalyzed Regio- and Stereoselective Aminoboration of Alkenylboronates

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Organic Letters
DOI: 10.1021/acs.orglett.6b02338

Datum: 20.09.2016


Cascade Reaction of Alkynols and 7-Oxabenzonorbornadienes Involving Transient Hemiketal Group Directed C–H Activation and Synergistic RhIII/ScIII Catalysis

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Organic Letters
DOI: 10.1021/acs.orglett.6b02587

Datum: 20.09.2016


Metathesis Reaction of Diazo Compounds and para-Quinone Methides for C–C Double Bond Formation: Synthesis of Tetrasubstituted Alkenes and Quinolinones

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Organic Letters
DOI: 10.1021/acs.orglett.6b02365

Datum: 20.09.2016


Total Synthesis of Grifolin, Grifolic Acid, LL-Z1272α, LL-Z1272β, and Ilicicolinic Acid A

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Organic Letters
DOI: 10.1021/acs.orglett.6b02469

Datum: 20.09.2016


Total Synthesis and Structural Reassignment of (±)-Cereoanhydride

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Organic Letters
DOI: 10.1021/acs.orglett.6b02424

Datum: 19.09.2016


Intramolecular Fischer Indole Synthesis for the Direct Synthesis of 3,4-Fused Tricyclic Indole and Application to the Total Synthesis of (−)-Aurantioclavine

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Organic Letters
DOI: 10.1021/acs.orglett.6b02541

Datum: 19.09.2016


Total Synthesis of Cytospolide D and Its Biomimetic Conversion to Cytospolides M, O, and Q

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Organic Letters
DOI: 10.1021/acs.orglett.6b02193

Datum: 16.09.2016


Modified Julia Olefination on Anhydrides: Extension and Limitations. Application to the Synthesis of Maculalactone B

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Organic Letters
DOI: 10.1021/acs.orglett.6b02160

Datum: 16.09.2016


De Novo Asymmetric Synthesis of Phoracantholide J

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Organic Letters
DOI: 10.1021/acs.orglett.6b02432

Datum: 16.09.2016


Photoredox Catalysis Mediated Application of Methyl Fluorosulfonyldifluoroacetate as the CF2CO2R Radical Source

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Organic Letters
DOI: 10.1021/acs.orglett.6b02580

Datum: 16.09.2016


Hydrogen Bonding Cluster-Enabled Addition of Sulfonic Acids to Haloalkynes: Access to Both (E)- and (Z)-Alkenyl Sulfonates

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Organic Letters
DOI: 10.1021/acs.orglett.6b02061

Datum: 15.09.2016


Two-Step Route to Diverse N-Functionalized Peptidomimetic-like Isatins through an Oxidation/Intramolecular Oxidative-Amidation Cascade of Ugi Azide and Ugi Three-Component Reaction Products

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Organic Letters
DOI: 10.1021/acs.orglett.6b02383

Datum: 15.09.2016


DNA Binding and Recognition of a CC Mismatch in a DNA Duplex by Water-Soluble Peptidocalix[4]arenes: Synthesis and Applications

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Organic Letters
DOI: 10.1021/acs.orglett.6b01995

Datum: 15.09.2016


Combining Ru-Catalyzed C–H Functionalization with Pd-Catalyzed Asymmetric Allylic Alkylation: Synthesis of 3-Allyl-3-aryl Oxindole Derivatives from Aryl α-Diazoamides

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Organic Letters
DOI: 10.1021/acs.orglett.6b02423

Datum: 15.09.2016


Gold-Catalyzed Intermolecular, anti-Markovnikov Hydroarylation of Methylenecyclopropanes with Indoles

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Organic Letters
DOI: 10.1021/acs.orglett.6b02431

Datum: 15.09.2016


Orthogonal Bodipy Trimers as Photosensitizers for Photodynamic Action

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Organic Letters
DOI: 10.1021/acs.orglett.6b02418

Datum: 15.09.2016


Aryne-Mediated [2,3]-Sigmatropic Rearrangement of Tertiary Allylic Amines

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Organic Letters
DOI: 10.1021/acs.orglett.6b02344

Datum: 15.09.2016


Biosynthesis of Shearinine: Diversification of a Tandem Prenyl Moiety of Fungal Indole Diterpenes

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Organic Letters
DOI: 10.1021/acs.orglett.6b02482

Datum: 15.09.2016


Photochemical Synthesis of Carbazoles Using an [Fe(phen)3](NTf2)2/O2 Catalyst System: Catalysis toward Sustainability

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Organic Letters
DOI: 10.1021/acs.orglett.6b02456

Datum: 14.09.2016


Asymmetric Hydrogenation of β-Aryloxy/Alkoxy Cinnamic Nitriles and Esters

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Organic Letters
DOI: 10.1021/acs.orglett.6b02393

Datum: 14.09.2016


Correction to “Generalized Anomeric Effect in gem-Diamines: Stereoselective Synthesis of α-N-Linked Disaccharide Mimics”

Organic Letters
DOI: 10.1021/acs.orglett.6b02614

Datum: 14.09.2016


Photochemical Formation of Dibenzosilacyclohept-4-yne for Cu-Free Click Chemistry with Azides and 1,2,4,5-Tetrazines

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Organic Letters
DOI: 10.1021/acs.orglett.6b02367

Datum: 14.09.2016


Functionalization of Azacalixaromatics by Cu(II)-Catalyzed Oxidative Cross-Coupling Reaction between the Arene C–H Bond and Boronic Acids

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Organic Letters
DOI: 10.1021/acs.orglett.6b02530

Datum: 14.09.2016


Direct Regioselective [3 + 2]-Cyclization Reactions of Ambivalent Electrophilic/Nucleophilic β-Chlorovinyl Dithianes: Access to Cyclopentene Derivatives

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Organic Letters
DOI: 10.1021/acs.orglett.6b02536

Datum: 14.09.2016


Pd-Catalyzed Intramolecular Cyclization via Direct C–H Addition to Nitriles: Skeletal Diverse Synthesis of Fused Polycyclic Indoles

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Organic Letters
DOI: 10.1021/acs.orglett.6b02460

Datum: 14.09.2016


Thiourea–Quaternary Ammonium Salt Catalyzed Asymmetric 1, 3-Dipolar Cycloaddition of Imino Esters To Construct Spiro[pyrrolidin-3,3′-oxindoles]

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Organic Letters
DOI: 10.1021/acs.orglett.6b02098

Datum: 14.09.2016


1,2-cis-α-Stereoselective Glycosylation Utilizing a Glycosyl-Acceptor-Derived Borinic Ester and Its Application to the Total Synthesis of Natural Glycosphingolipids

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Organic Letters
DOI: 10.1021/acs.orglett.6b02488

Datum: 14.09.2016


Correction to “Gold(I)-Catalyzed Domino Cyclizations of Diynes for the Synthesis of Functionalized Cyclohexenone Derivatives. Total Synthesis of (−)-Gabosine H and (−)-6-epi-Gabosine H”

Organic Letters
DOI: 10.1021/acs.orglett.6b02509

Datum: 14.09.2016


Kanamienamide, an Enamide with an Enol Ether from the Marine Cyanobacterium Moorea bouillonii

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Organic Letters
DOI: 10.1021/acs.orglett.6b02364

Datum: 13.09.2016


Organocatalytic Asymmetric Cascade Reaction of 2-Hydroxyphenyl-Substituted Enones and Isocyanates To Construct 1,3-Benzoxazin-2-ones

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Organic Letters
DOI: 10.1021/acs.orglett.6b02522

Datum: 13.09.2016


Regioselective Synthesis of 2,3,4-Trisubstituted Pyrroles via Pd(II)-Catalyzed Three-Component Cascade Reactions of Amines, Alkyne Esters, and Alkenes

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Organic Letters
DOI: 10.1021/acs.orglett.6b02325

Datum: 13.09.2016


Copper(I)-Catalyzed Ketone, Amine, and Alkyne Coupling for the Synthesis of 2-Alkynylpyrrolidines and -piperidines

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Organic Letters
DOI: 10.1021/acs.orglett.6b02127

Datum: 13.09.2016


Functionalization of Alkenes through Telescoped Continuous Flow Aziridination Processes

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Organic Letters
DOI: 10.1021/acs.orglett.6b02349

Datum: 13.09.2016


Total Synthesis and Structural Revision of (+)-Yaoshanenolide B

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Organic Letters
DOI: 10.1021/acs.orglett.6b02446

Datum: 13.09.2016


Metal-Free Visible-Light-Mediated Oxidative Cross-Coupling of Thiols with P(O)H Compounds Using Air as the Oxidant

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Organic Letters
DOI: 10.1021/acs.orglett.6b02563

Datum: 13.09.2016


Catalytic Enantioselective Total Synthesis of Hypocrolide A

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Organic Letters
DOI: 10.1021/acs.orglett.6b02414

Datum: 13.09.2016


Convergent Synthesis of N-Linked Glycopeptides via Aminolysis of ω-Asp p-Nitrophenyl Thioesters in Solution

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Organic Letters
DOI: 10.1021/acs.orglett.6b02288

Datum: 13.09.2016


Enantioselective Synthesis of Quaternary Stereocenters via Chromium Catalysis

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Organic Letters
DOI: 10.1021/acs.orglett.6b02540

Datum: 13.09.2016


Cu-Click Compatible Triazabutadienes To Expand the Scope of Aryl Diazonium Ion Chemistry

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Organic Letters
DOI: 10.1021/acs.orglett.6b02420

Datum: 13.09.2016


Phosphine-Triggered Selectivity Switch in Silver-Catalyzed o-Alkynylbenzohydroxamic Acid Cycloisomerizations

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Organic Letters
DOI: 10.1021/acs.orglett.6b02235

Datum: 12.09.2016


Synthesis of 2-Ethenylcyclopropyl Aryl Ketones via Intramolecular SN2-like Displacement of an Ester

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Organic Letters
DOI: 10.1021/acs.orglett.6b02588

Datum: 12.09.2016


A Three-Component Reaction for the Synthesis of 1-Azabicyclo[3.1.0]hexane-3-enes

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Organic Letters
DOI: 10.1021/acs.orglett.6b02180

Datum: 12.09.2016


Generation of Hydrogen from Water: A Pd-Catalyzed Reduction of Water Using Diboron Reagent at Ambient Conditions

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Organic Letters
DOI: 10.1021/acs.orglett.6b02508

Datum: 12.09.2016


Copper-Catalyzed Decarboxylative Atom Transfer Radical Addition of Iododifluoroacetate to Alkynyl Carboxylic Acids

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Organic Letters
DOI: 10.1021/acs.orglett.6b02216

Datum: 12.09.2016


Palladium-Catalyzed Cascade Arene/Alkyne Annulation: Synthesis of Fluorene-Benzoxazine Derivatives

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Organic Letters
DOI: 10.1021/acs.orglett.6b02224

Datum: 12.09.2016


Cleavable β-Cyanoethyl Isocyanide in the Ugi Tetrazole Reaction

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Organic Letters
DOI: 10.1021/acs.orglett.6b01826

Datum: 09.09.2016


A Disulfonimide Catalyst for Highly Enantioselective Mukaiyama–Mannich Reaction

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Organic Letters
DOI: 10.1021/acs.orglett.6b02262

Datum: 09.09.2016


Selective Derivatization of N-Terminal Cysteines Using Cyclopentenediones

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Organic Letters
DOI: 10.1021/acs.orglett.6b02301

Datum: 09.09.2016


Gold-Catalyzed cis-Hydroarylation of Ynamides with Indoles: Regio- and Stereoselective Synthesis of a Class of 2-Vinylindoles

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Organic Letters
DOI: 10.1021/acs.orglett.6b02189

Datum: 09.09.2016


Multicomponent Coupling Reaction of Perfluoroarenes with 1,3-Butadiene and Aryl Grignard Reagents Promoted by an Anionic Ni(II) Complex

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Organic Letters
DOI: 10.1021/acs.orglett.6b02343

Datum: 09.09.2016


Structure Revision of an Acorane Sesquiterpene Cordycepol A

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Organic Letters
DOI: 10.1021/acs.orglett.6b02341

Datum: 09.09.2016


Divergent Reactivity of Nitrocyclopropanes with Huisgen Zwitterions and Facile Syntheses of 3-Alkoxy Pyrazolines and Pyrazoles

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Organic Letters
DOI: 10.1021/acs.orglett.6b02415

Datum: 09.09.2016


Nickel-Catalyzed Site-Selective C–H Bond Difluoroalkylation of 8-Aminoquinolines on the C5-Position

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Organic Letters
DOI: 10.1021/acs.orglett.6b02166

Datum: 09.09.2016


Palladium-Catalyzed Ylidyl-Carbonylation of Aryl Halides To Produce α-Acylphosphoranes

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Organic Letters
DOI: 10.1021/acs.orglett.6b02278

Datum: 09.09.2016


Synthesis of β-Difluoroalkylated Acrylonitriles in the Presence of Copper Powder

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Organic Letters
DOI: 10.1021/acs.orglett.6b02627

Datum: 08.09.2016


Arylation, Vinylation, and Alkynylation of Electron-Deficient (Hetero)arenes Using Iodonium Salts

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Organic Letters
DOI: 10.1021/acs.orglett.6b02550

Datum: 08.09.2016


Rhodium(II)-Alkynyl Carbenoids Insertion into Si–H bonds: An Entry to Propargylic Geminal Bis(silanes)

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Organic Letters
DOI: 10.1021/acs.orglett.6b02264

Datum: 07.09.2016






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