Organic Letters

Current research reports and chronological list of recent articles.


The international scientific journal Organic Letters serves as the international forum for the communication of important research in all branches of the theory and practice of: organic chemistry (including organometallic and materials chemistry); physical and theoretical organic chemistry; natural products isolation and synthesis; new synthetic methodology; bioorganic and medicinal chemistry.

The publisher is the American Chemical Society, ACS. The copyright and publishing rights of specialized products listed below are in this publishing house. This is also responsible for the content shown.

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Additional research articles see Current Chemistry Research Articles. Magazines with similar content (organic chemistry):

 - Beilstein Journal of Organic Chemistry.

 - European Journal of Organic Chemistry.

 - Journal of Organic Chemistry.

 - Journal of Physical Organic Chemistry.

 - Organic Process Research and Development.

 - Russian Journal of Organic Chemistry.

 - Synlett.



Organic Letters - Abstracts



Chemo- and Regioselective Direct Functional Group Installation through Catalytic Hydroxy Group Selective Conjugate Addition of Amino Alcohols to α,β-Unsaturated Sulfonyl Compounds

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Organic Letters
DOI: 10.1021/acs.orglett.6b01464

Datum: 30.06.2016


Melonoside A: An ω-Glycosylated Fatty Acid Amide from the Far Eastern Marine Sponge Melonanchora kobjakovae

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Organic Letters
DOI: 10.1021/acs.orglett.6b01678

Datum: 30.06.2016


Developing a Biocascade Process: Concurrent Ketone Reduction-Nitrile Hydrolysis of 2-Oxocycloalkanecarbonitriles

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Organic Letters
DOI: 10.1021/acs.orglett.6b01510

Datum: 30.06.2016


Ruthenium-Catalyzed C–H Alkynylation of Aromatic Amides with Hypervalent Iodine–Alkyne Reagents

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Organic Letters
DOI: 10.1021/acs.orglett.6b01281

Datum: 30.06.2016


Asymmetric Total Synthesis of Kopsiyunnanine K, a Monoterpenoid Indole Alkaloid with a Rearranged Skeleton

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Organic Letters
DOI: 10.1021/acs.orglett.6b01704

Datum: 29.06.2016


Palladium-Catalyzed Internal Nucleophile-Assisted Hydration–Olefin Insertion Cascade: Diastereoselective Synthesis of 2,3-Dihydro-1H-inden-1-ones

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Organic Letters
DOI: 10.1021/acs.orglett.6b01623

Datum: 29.06.2016


Synthesis of Fasicularin

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Organic Letters
DOI: 10.1021/acs.orglett.6b01669

Datum: 29.06.2016


Synthesis of 1,3-Dienes via a Sequential Suzuki–Miyaura Coupling/Palladium-Mediated Allene Isomerization Sequence

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Organic Letters
DOI: 10.1021/acs.orglett.6b01841

Datum: 29.06.2016


AgSCF3-Mediated Oxidative Trifluoromethythiolation of Alkynes with Dearomatization to Synthesize SCF3-Substituted Spiro[4,5]trienones

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Organic Letters
DOI: 10.1021/acs.orglett.6b01702

Datum: 29.06.2016


Co(II) PCP Pincer Complexes as Catalysts for the Alkylation of Aromatic Amines with Primary Alcohols

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Organic Letters
DOI: 10.1021/acs.orglett.6b01647

Datum: 29.06.2016


Exploiting Alkylquinone Tautomerization: Amine Benzylation

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Organic Letters
DOI: 10.1021/acs.orglett.6b01629

Datum: 28.06.2016


Ruthenium-Catalyzed Regioselective 1,4-Hydroboration of Pyridines

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Organic Letters
DOI: 10.1021/acs.orglett.6b01564

Datum: 28.06.2016


Unexpected Reactivity of Trifluoromethyl Diazomethane (CF3CHN2): Electrophilicity of the Terminal N-Atom

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Organic Letters
DOI: 10.1021/acs.orglett.6b01565

Datum: 28.06.2016


Synthesis of Functionalized Pyridines via a Regioselective Oxazoline Promoted C–H Amidation Reaction

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Organic Letters
DOI: 10.1021/acs.orglett.6b01612

Datum: 28.06.2016


Chiral Phosphoric Acid Catalyzed [3 + 2] Cycloaddition and Tandem Oxidative [3 + 2] Cycloaddition: Asymmetric Synthesis of Substituted 3-Aminodihydrobenzofurans

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Organic Letters
DOI: 10.1021/acs.orglett.6b01593

Datum: 28.06.2016


Solvent-Controlled, Tunable β-OAc and β-H Elimination in Rh(III)-Catalyzed Allyl Acetate and Aryl Amide Coupling via C–H Activation

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Organic Letters
DOI: 10.1021/acs.orglett.6b01566

Datum: 28.06.2016


Synthesis of 1-Substituted Isoquinolines by Heterocyclization of TosMIC Derivatives: Total Synthesis of Cassiarin A

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Organic Letters
DOI: 10.1021/acs.orglett.6b01521

Datum: 28.06.2016


Copper-Catalyzed Cascade Substitution/Cyclization of N-Isocyanates: A Synthesis of 1-Aminobenzimidazolones

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Organic Letters
DOI: 10.1021/acs.orglett.6b01686

Datum: 24.06.2016


A Series of β-Carboline Alkaloids from the Seeds of Peganum harmala Show G-Quadruplex Interactions

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Organic Letters
DOI: 10.1021/acs.orglett.6b01560

Datum: 24.06.2016


tert-Butyl Hydroperoxide (TBHP)-Initiated Vicinal Sulfonamination of Alkynes: A Radical Annulation toward 3-Sulfonylindoles

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Organic Letters
DOI: 10.1021/acs.orglett.6b01427

Datum: 24.06.2016


Siladifluoromethylation and Difluoromethylation onto C(sp3), C(sp2), and C(sp) Centers Using Ruppert–Prakash Reagent and Fluoroform

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Organic Letters
DOI: 10.1021/acs.orglett.6b01476

Datum: 24.06.2016


Naquihexcin A, a S-Bridged Pyranonaphthoquinone Dimer Bearing an Unsaturated Hexuronic Acid Moiety from a Sponge-Derived Streptomyces sp. HDN-10-293

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Organic Letters
DOI: 10.1021/acs.orglett.6b01485

Datum: 24.06.2016


Artaboterpenoids A and B, Bisabolene-Derived Sesquiterpenoids from Artabotrys hexapetalus

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Organic Letters
DOI: 10.1021/acs.orglett.6b01519

Datum: 24.06.2016


Pseudoxylallemycins A–F, Cyclic Tetrapeptides with Rare Allenyl Modifications Isolated from Pseudoxylaria sp. X802: A Competitor of Fungus-Growing Termite Cultivars

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Organic Letters
DOI: 10.1021/acs.orglett.6b01437

Datum: 24.06.2016


Total Syntheses of (+)-Marrubiin and (−)-Marrulibacetal

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Organic Letters
DOI: 10.1021/acs.orglett.6b01602

Datum: 24.06.2016


Solution to the C3–Arylation of Indazoles: Development of a Scalable Method

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Organic Letters
DOI: 10.1021/acs.orglett.6b01456

Datum: 23.06.2016


2-Pyridinyl-N-(2,4-difluorobenzyl)aminoethyl Group As Thermocontrolled Implement for Protection of Carboxylic Acids

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Organic Letters
DOI: 10.1021/acs.orglett.6b01475

Datum: 23.06.2016


Convergent Synthesis of Diverse Nitrogen Heterocycles via Rh(III)-Catalyzed C–H Conjugate Addition/Cyclization Reactions

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Organic Letters
DOI: 10.1021/acs.orglett.6b01611

Datum: 23.06.2016


Cascade Photoredox/Iodide Catalysis: Access to Difluoro-γ-lactams via Aminodifluoroalkylation of Alkenes

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Organic Letters
DOI: 10.1021/acs.orglett.6b01515

Datum: 23.06.2016


Stereocontrolled Photoinduced Glycosylation Using an Aryl Thiourea as an Organo photoacid

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Organic Letters
DOI: 10.1021/acs.orglett.6b01404

Datum: 23.06.2016


Selective Metal-Free Deoxygenation of Unsymmetrical 1,2-Dicarbonyl Compounds by Chlorotrimethylsilane and Sodium Iodide

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Organic Letters
DOI: 10.1021/acs.orglett.6b01491

Datum: 23.06.2016


Nucleophilic Difluoromethylation Using (Bromodifluoromethyl)trimethylsilane

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Organic Letters
DOI: 10.1021/acs.orglett.6b01641

Datum: 23.06.2016


Enantioselective Synthesis of Both Epimers at C-21 in the Proposed Structure of Cytotoxic Macrolide Callyspongiolide

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Organic Letters
DOI: 10.1021/acs.orglett.6b01523

Datum: 22.06.2016


Synthesis of Substituted 4-, 5-, 6-, and 7-Azaindoles from Aminopyridines via a Cascade C–N Cross-Coupling/Heck Reaction

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Organic Letters
DOI: 10.1021/acs.orglett.6b01500

Datum: 22.06.2016


Enantioselective Synthesis of Guaianolides in the Osmitopsin Family by Domino Metathesis

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Organic Letters
DOI: 10.1021/acs.orglett.6b01619

Datum: 22.06.2016


Development of a Coordinatively Unsaturated Chiral Indenylruthenium Catalyst

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Organic Letters
DOI: 10.1021/acs.orglett.6b01375

Datum: 22.06.2016


Enantioselective Intermolecular C–H Functionalization of Allylic and Benzylic sp3 C–H Bonds Using N-Sulfonyl-1,2,3-triazoles

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Organic Letters
DOI: 10.1021/acs.orglett.6b01298

Datum: 22.06.2016


Dimethyl Sulfoxide and N-Iodosuccinimide Promoted 5-exo-dig Oxidative Cyclization of Yne-Tethered Ynamide: Access to Pyrrolidones and Spiro-pyrrolidones

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Organic Letters
DOI: 10.1021/acs.orglett.6b01149

Datum: 22.06.2016


A Macrocyclic 1,4-Diketone Enables the Synthesis of a p-Phenylene Ring That Is More Strained than a Monomer Unit of [4]Cycloparaphenylene

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Organic Letters
DOI: 10.1021/acs.orglett.6b01536

Datum: 22.06.2016


Total Synthesis of the Marine Natural Product Solomonamide B Necessitates Stereochemical Revision

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Organic Letters
DOI: 10.1021/acs.orglett.6b01395

Datum: 22.06.2016


A Chiral Phosphoramidite Reagent for the Synthesis of Inositol Phosphates

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Organic Letters
DOI: 10.1021/acs.orglett.6b01374

Datum: 22.06.2016


ortho-Heteroarylation of Azobenzenes by Rh-Catalyzed Cross-Dehydrogenative Coupling: An Approach to Conjugated Biaryls

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Organic Letters
DOI: 10.1021/acs.orglett.6b01277

Datum: 22.06.2016


Chiral Brønsted Acid Catalyzed Enantioselective Phosphonylation of Allylamine via Oxidative Dehydrogenation Coupling

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Organic Letters
DOI: 10.1021/acs.orglett.6b01514

Datum: 22.06.2016


Gold-Catalyzed Intermolecular Ynamide Amination-Initiated Aza-Nazarov Cyclization: Access to Functionalized 2-Aminopyrroles

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Organic Letters
DOI: 10.1021/acs.orglett.6b01503

Datum: 22.06.2016


Accessing Benzimidazoles via a Ring Distortion Strategy: An Oxone Mediated Tandem Reaction of 2-Aminobenzylamines

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Organic Letters
DOI: 10.1021/acs.orglett.6b01217

Datum: 22.06.2016


Tunable P-Chiral Bisdihydrobenzooxaphosphole Ligands for Enantioselective Hydroformylation

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Organic Letters
DOI: 10.1021/acs.orglett.6b01452

Datum: 22.06.2016


Selective Rhodium-Catalyzed Hydroformylation of Alkynes to α,β-Unsaturated Aldehydes with a Tetraphosphoramidite Ligand

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Organic Letters
DOI: 10.1021/acs.orglett.6b01605

Datum: 22.06.2016


Correction to Enantioselective Total Synthesis of (+)-Amphirionin-4

Organic Letters
DOI: 10.1021/acs.orglett.6b01620

Datum: 22.06.2016


I2/TBHP Mediated C–N and C–H Bond Cleavage of Tertiary Amines toward Selective Synthesis of Sulfonamides and β-Arylsulfonyl Enamines: The Solvent Effect on Reaction

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Organic Letters
DOI: 10.1021/acs.orglett.6b01412

Datum: 21.06.2016


Chiral N-Heterocyclic Carbene Ligand Enabled Nickel(0)-Catalyzed Enantioselective Three-Component Couplings as Direct Access to Silylated Indanols

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Organic Letters
DOI: 10.1021/acs.orglett.6b01492

Datum: 21.06.2016


Organocascade Synthesis of Annulated (Z)-2-Methylenepyrans: Nucleophilic Conjugate Addition of Hydroxycoumarins and Pyranone to Branched Nitro Enynes via Allene Formation/Oxa-Michael Cyclization/Alkene Isomerization Sequence

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Organic Letters
DOI: 10.1021/acs.orglett.6b01265

Datum: 21.06.2016


Functionalized O6–Corona[6]arenes: Synthesis, Structure, and Fullerene Complexation Property

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Organic Letters
DOI: 10.1021/acs.orglett.6b01330

Datum: 21.06.2016


Synthesis and Reactivity of Triazaphenanthrenes

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Organic Letters
DOI: 10.1021/acs.orglett.6b01373

Datum: 20.06.2016


Alkene Dioxygenation with Malonoyl Peroxides: Synthesis of γ-Lactones, Isobenzofuranones, and Tetrahydrofurans

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Organic Letters
DOI: 10.1021/acs.orglett.6b01253

Datum: 17.06.2016


Visible-Light-Induced Arylthiofluoroalkylations of Unactivated Heteroaromatics and Alkenes

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Organic Letters
DOI: 10.1021/acs.orglett.6b01495

Datum: 17.06.2016


Pd-Catalyzed and Copper Assisted Regioselective Sequential C2 and C7 Arylation of Thiazolo[5,4-f]quinazolin-9(8H)-one with Aryl Halides

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Organic Letters
DOI: 10.1021/acs.orglett.6b01552

Datum: 17.06.2016


Stereoselective Synthesis of Alkylidene Phthalides

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Organic Letters
DOI: 10.1021/acs.orglett.6b01203

Datum: 17.06.2016


Catalyst-Free Halogenation of α-Diazocarbonyl Compounds with N-Halosuccinimides: Synthesis of 3-Halooxindoles or Vinyl Halides

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Organic Letters
DOI: 10.1021/acs.orglett.6b01346

Datum: 16.06.2016


Cu(I)-Catalyzed Enantioselective Friedel–Crafts Alkylation of Indoles with 2-Aryl-N-sulfonylaziridines as Alkylating Agents

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Organic Letters
DOI: 10.1021/acs.orglett.6b01317

Datum: 16.06.2016


Copper-Catalyzed 8-Aminoquinoline-Directed Selenylation of Arene and Heteroarene C–H Bonds

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Organic Letters
DOI: 10.1021/acs.orglett.6b01420

Datum: 16.06.2016


Synthesis of an ABCD-Type Phthalocyanine by Intramolecular Cyclization Reaction

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Organic Letters
DOI: 10.1021/acs.orglett.6b01489

Datum: 16.06.2016


Chemoselective Dimerization of Phosphates

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Organic Letters
DOI: 10.1021/acs.orglett.6b01466

Datum: 16.06.2016


Cascade C–H Functionalization/Amidation Reaction for Synthesis of Azepinone Derivatives

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Organic Letters
DOI: 10.1021/acs.orglett.6b01140

Datum: 16.06.2016


Modular, Catalytic Enantioselective Construction of Quaternary Carbon Stereocenters by Sequential Cross-Coupling Reactions

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Organic Letters
DOI: 10.1021/acs.orglett.6b01580

Datum: 16.06.2016


2,5-Oxyarylation of Furans: Synthesis of Spiroacetals via Palladium-Catalyzed Aerobic Oxidative Coupling of Boronic Acids with α-Hydroxyalkylfurans

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Organic Letters
DOI: 10.1021/acs.orglett.6b01472

Datum: 16.06.2016


Catalytic Oxidative Carbene Coupling of α-Diazo Carbonyls for the Synthesis of β-Amino Ketones via C(sp3)–H Functionalization

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Organic Letters
DOI: 10.1021/acs.orglett.6b01189

Datum: 16.06.2016


Detrifluoroacetylative in Situ Generation of Free 3-Fluoroindolin-2-one-Derived Tertiary Enolates: Design, Synthesis, and Assessment of Reactivity toward Asymmetric Mannich Reactions

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Organic Letters
DOI: 10.1021/acs.orglett.6b01516

Datum: 15.06.2016


Oxidative Radical Addition–Cyclization of Sulfonyl Hydrazones with Simple Olefins by Binary Acid Catalysis

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Organic Letters
DOI: 10.1021/acs.orglett.6b01360

Datum: 15.06.2016


Intramolecular Imidoylative Heck Reaction: Synthesis of Cyclic Ketoimines from Functionalized Isocyanide

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Organic Letters
DOI: 10.1021/acs.orglett.6b01174

Datum: 15.06.2016


Metal-Free Oxidative Annulation of 2-Naphthols with Terminal Alkynes Affording 2-Arylnaphtho[2,1-b]furans

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Organic Letters
DOI: 10.1021/acs.orglett.6b01352

Datum: 15.06.2016


Solution and Solid-Phase Stereocontrolled Synthesis of 1,2-cis-Glycopyranosides with Minimally Protected Glycopyranosyl Donors Catalyzed by BF3–N,N-Dimethylformamide Complex

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Organic Letters
DOI: 10.1021/acs.orglett.6b01263

Datum: 15.06.2016


Catalyst-Free Singlet Oxygen-Promoted Decarboxylative Amidation of α-Keto Acids with Free Amines

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Organic Letters
DOI: 10.1021/acs.orglett.6b01296

Datum: 15.06.2016


Diamination of Domino Aryne Precursor with Sulfonamides

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Organic Letters
DOI: 10.1021/acs.orglett.6b01334

Datum: 15.06.2016


Copper-Catalyzed Direct Propargylation of Polyfluoroarenes with Secondary Propargyl Phosphates

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Organic Letters
DOI: 10.1021/acs.orglett.6b01642

Datum: 14.06.2016


Synthesis and Photophysical Properties of Fluorescence Molecular Probe for Turn-ON-Type Detection of Cytosine Bulge DNA

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Organic Letters
DOI: 10.1021/acs.orglett.6b01378

Datum: 14.06.2016


Synthesis of the C9–C25 Subunit of Spirastrellolide B

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Organic Letters
DOI: 10.1021/acs.orglett.6b01248

Datum: 14.06.2016


Ruthenium-Catalyzed Dehydrogenative β-Benzylation of 1,2,3,4-Tetrahydroquinolines with Aryl Aldehydes: Access to Functionalized Quinolines

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Organic Letters
DOI: 10.1021/acs.orglett.6b01390

Datum: 14.06.2016


Sulfinamide Phosphinates as Chiral Catalysts for the Enantioselective Organocatalytic Reduction of Imines

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Organic Letters
DOI: 10.1021/acs.orglett.6b01509

Datum: 14.06.2016


Conformational Control of Chiral Amido-Thiourea Catalysts Enables Improved Activity and Enantioselectivity

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Organic Letters
DOI: 10.1021/acs.orglett.6b01435

Datum: 13.06.2016


Synthesis of Quaternary 3,3-Disubstituted 2-Oxindoles from 2-Substituted Indole Using Selectfluor

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Organic Letters
DOI: 10.1021/acs.orglett.6b01367

Datum: 13.06.2016


Stereoselection in Intramolecular Diels–Alder Reactions of 2-Cyano-1-azadienes: Indolizidine and Quinolizidine Synthesis

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Organic Letters
DOI: 10.1021/acs.orglett.6b00881

Datum: 13.06.2016


Synthesis of Chiral Piperazines via Hydrogenation of Pyrazines Activated by Alkyl Halides

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Organic Letters
DOI: 10.1021/acs.orglett.6b01190

Datum: 13.06.2016


One-Pot Synthesis of 5-Hydroxy-4H-1,3-thiazin-4-ones: Structure Revision, Synthesis, and NMR Shift Dependence of Thiasporine A

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Organic Letters
DOI: 10.1021/acs.orglett.6b01166

Datum: 10.06.2016


Metal-Free Oxidative 1,2-Arylmethylation Cascades of N-(Arylsulfonyl)acrylamides Using Peroxides as the Methyl Resource

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Organic Letters
DOI: 10.1021/acs.orglett.6b01419

Datum: 10.06.2016


Isocyano Enones: Addition–Cyclization Cascade to Oxazoles

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Organic Letters
DOI: 10.1021/acs.orglett.6b01147

Datum: 10.06.2016


Bis-corannulenoanthracene: An Angularly Fused Pentacene as a Precursor for Barrelene-Tethered Receptors for Fullerenes

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Organic Letters
DOI: 10.1021/acs.orglett.6b01049

Datum: 09.06.2016


Regiocontrolled Oxidative C–C Coupling of Dienol Ethers and 1,3-Dicarbonyl Compounds

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Organic Letters
DOI: 10.1021/acs.orglett.6b01397

Datum: 09.06.2016


Hydroxyl-Assisted Carbonylation of Alkenyltin Derivatives: Development and Application to a Formal Synthesis of Tubelactomicin A

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Organic Letters
DOI: 10.1021/acs.orglett.6b01431

Datum: 09.06.2016


Dihydrooxazine N-Oxide Intermediates as Resting States in Organocatalytic Kinetic Resolution of Functionalized Nitroallylic Amines with Aldehydes

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Organic Letters
DOI: 10.1021/acs.orglett.6b00493

Datum: 09.06.2016


Toward Leiodermatolide: Synthesis of the Core Structure

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Organic Letters
DOI: 10.1021/acs.orglett.6b01355

Datum: 09.06.2016


A Light-Induced Vinylogous Nazarov-Type Cyclization

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Organic Letters
DOI: 10.1021/acs.orglett.6b01449

Datum: 09.06.2016


Air-Stable Triazine-Based Ni(II) PNP Pincer Complexes As Catalysts for the Suzuki–Miyaura Cross-Coupling

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Organic Letters
DOI: 10.1021/acs.orglett.6b01398

Datum: 09.06.2016


Direct Nucleophilic Difluoromethylation of Carbonyl Compounds

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Organic Letters
DOI: 10.1021/acs.orglett.6b01425

Datum: 09.06.2016


Palladium/Silver Synergistic Catalysis in Direct Aerobic Carbonylation of C(sp2)−H Bonds Using DMF as a Carbon Source: Synthesis of Pyrido-Fused Quinazolinones and Phenanthridinones

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Organic Letters
DOI: 10.1021/acs.orglett.6b01292

Datum: 08.06.2016


Correction to “Diastereoselective Passerini Reaction of Biobased Chiral Aldehydes: Divergent Synthesis of Various Polyfunctionalized Heterocycles”

Organic Letters
DOI: 10.1021/acs.orglett.6b01574

Datum: 08.06.2016






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