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Journal of Organic Chemistry - Current Research Articles



Current research articles: Organic Chemistry

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Journal of Organic Chemistry - Editor: American Chemical Society, ACS

JOC welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry.




Current articles of the journal:



Structure–Reactivity Relationship of Trifluoromethanesulfenates: Discovery of an Electrophilic Trifluoromethylthiolating Reagent

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The Journal of Organic Chemistry
DOI: 10.1021/jo502645m

Posted on 3 March 2015 | 7:29 pm


Anion Receptors Based on Halogen Bonding with Halo-1,2,3-triazoliums

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00028

Posted on 3 March 2015 | 2:38 pm


Kinetic Resolution of ?-Methylene-?-hydroxy Esters Catalyzed by Acyl Transfer Catalyst An-PIQ

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00073

Posted on 2 March 2015 | 8:49 pm


Mechanistic Insight into the Dehydro-Diels–Alder Reaction of Styrene–Ynes

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00200

Posted on 2 March 2015 | 3:49 pm


Rhodium-Catalyzed 1,4-Addition of Arylboronic Acids to 3-Benzylidene-1H-pyrrolo[2,3-b]pyridin-2(3H)-one Derivatives

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The Journal of Organic Chemistry
DOI: 10.1021/jo502784h

Posted on 2 March 2015 | 1:07 pm


Rh(I)-Catalyzed Chemo- and Stereoselective Domino Cycloaddition of Optically Active Propargyl 2,4-Hexadienyl Ethers

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00150

Posted on 2 March 2015 | 1:07 pm


Computational Mechanistic Study of the Julia–Kocien?ski Reaction

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00008

Posted on 27 February 2015 | 9:03 pm


Synthesis of 1,2-Borazaronaphthalenes from Imines by Base-Promoted Borylation of C–H bond

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The Journal of Organic Chemistry
DOI: 10.1021/jo5029437

Posted on 27 February 2015 | 2:58 pm


Brønsted Acid Catalyzed Asymmetric Diels–Alder Reactions: Stereoselective Construction of Spiro[tetrahydrocarbazole-3,3?-oxindole] Framework

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00198

Posted on 27 February 2015 | 2:38 pm


Indium(III)-Catalyzed Knoevenagel Condensation of Aldehydes and Activated Methylenes Using Acetic Anhydride as a Promoter

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00011

Posted on 26 February 2015 | 8:37 pm


Pd-Catalyzed Directed ortho-C–H Alkenylation of Phenylalanine Derivatives

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The Journal of Organic Chemistry
DOI: 10.1021/jo502912m

Posted on 26 February 2015 | 8:37 pm


Construction of Chiral ?-Amino Quaternary Stereogenic Centers via Phase-Transfer Catalyzed Enantioselective ?-Alkylation of ?-Amidomalonates

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The Journal of Organic Chemistry
DOI: 10.1021/jo502791d

Posted on 26 February 2015 | 8:34 pm


Origin of High E-Selectivity in 4-Pyrrolidinopyridine-Catalyzed Tetrasubstituted ?,??-Alkenediol: A Computational and Experimental Study

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The Journal of Organic Chemistry
DOI: 10.1021/jo5029453

Posted on 26 February 2015 | 8:32 pm


Iridium-Catalyzed Direct Synthesis of Tryptamine Derivatives from Indoles: Exploiting N-Protected ?-Amino Alcohols as Alkylating Agents

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00195

Posted on 26 February 2015 | 8:30 pm


Synthesis of Substituted Resorcinol Monomethyl Ethers from 2-Bromo-3-methoxycyclohex-2-en-1-ones

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00192

Posted on 26 February 2015 | 5:57 pm


Aminobenzofuran-Fused Rhodamine Dyes with Deep-Red to Near-Infrared Emission for Biological Applications

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00077

Posted on 26 February 2015 | 5:08 pm


Taming Chlorine Azide: Access to 1,2-Azidochlorides from Alkenes

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00009

Posted on 26 February 2015 | 2:36 pm


Synthesis of Quinolinones with Palladium-Catalyzed Oxidative Annulation between Acrylamides and Arynes

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The Journal of Organic Chemistry
DOI: 10.1021/jo5027673

Posted on 25 February 2015 | 10:27 pm


Base-Promoted Transannulation of Heterocyclic Enamines and 2,3-Epoxypropan-1-ones: Regio- and Stereoselective Synthesis of Fused Pyridines and Pyrroles

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00067

Posted on 25 February 2015 | 10:26 pm


Light-Enabled Synthesis of Anhydrides and Amides

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00003

Posted on 25 February 2015 | 8:55 pm


Photoremoval of Protecting Groups: Mechanistic Aspects of 1,3-Dithiane Conversion to a Carbonyl Group

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The Journal of Organic Chemistry
DOI: 10.1021/jo502953t

Posted on 25 February 2015 | 5:54 pm


?-Shaped Bis(areno)-1,4-dihydropyrrolo[3,2-b]pyrroles Generated by Oxidative Aromatic Coupling

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00052

Posted on 25 February 2015 | 5:52 pm


Cs2CO3-Promoted Carboxylation of N-Tosylhydrazones with Carbon Dioxide toward ?-Arylacrylic Acids

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The Journal of Organic Chemistry
DOI: 10.1021/jo502908v

Posted on 25 February 2015 | 2:57 pm


Theoretical Examination of the S–C–P Anomeric Effect

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The Journal of Organic Chemistry
DOI: 10.1021/jo5029425

Posted on 25 February 2015 | 2:18 pm


Engaging Nonaromatic, Heterocyclic Tosylates in Reductive Cross-Coupling with Aryl and Heteroaryl Bromides

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00135

Posted on 25 February 2015 | 2:09 pm


Reactivity and Stereoselectivity of 6? and Nazarov Electrocyclizations of Bridged Bicyclic Trienes and Divinyl Ketones

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00070

Posted on 24 February 2015 | 8:04 pm


Dual Role of Acetanilides: Traceless Removal of a Directing Group through Deacetylation/Diazotation and Palladium-Catalyzed C–C-Coupling Reactions

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00272

Posted on 24 February 2015 | 7:03 pm


Preparation of Flavocoenzyme Isotopologues by Biotransformation of Purines

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The Journal of Organic Chemistry
DOI: 10.1021/jo502480w

Posted on 24 February 2015 | 5:55 pm


Reactivity-Based Dynamic Covalent Chemistry: Reversible Binding and Chirality Discrimination of Monoalcohols

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The Journal of Organic Chemistry
DOI: 10.1021/jo502801g

Posted on 24 February 2015 | 4:43 pm


Metal-Free Arylation of Ethyl Acetoacetate with Hypervalent Diaryliodonium Salts: An Immediate Access to Diverse 3-Aryl-4(1H)-Quinolones

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The Journal of Organic Chemistry
DOI: 10.1021/jo5023958

Posted on 24 February 2015 | 4:40 pm


Tools for Identifying Gelator Scaffolds and Solvents

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The Journal of Organic Chemistry
DOI: 10.1021/jo502915w

Posted on 24 February 2015 | 1:21 pm


Synthesis of Vinyl Trifluoromethyl Thioethers via Copper-Mediated Trifluoromethylthiolation of Vinyl Bromides

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00144

Posted on 24 February 2015 | 6:35 am


Synthesis of Mimics of Pramanicin from Pyroglutamic Acid and Their Antibacterial Activity

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The Journal of Organic Chemistry
DOI: 10.1021/jo502810b

Posted on 23 February 2015 | 8:15 pm


Multicomponent Synthesis of Substituted and Fused-Ring Imidazoles via Phospha-mu?nchnone Cycloaddition

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The Journal of Organic Chemistry
DOI: 10.1021/jo5028936

Posted on 23 February 2015 | 7:05 pm


Rhodium-Catalyzed Dehydrogenative Coupling of Phenylheteroarenes with Alkynes or Alkenes

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00155

Posted on 23 February 2015 | 5:26 pm


Aza-Wacker-Type Reaction between Electron-Deficient Olefins and N-Alkylsulfonamides

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The Journal of Organic Chemistry
DOI: 10.1021/jo502823m

Posted on 23 February 2015 | 3:16 pm


Synthesis of 2-(3?-Indolyl)tetrahydrofurans by Oxidative Cycloetherification

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00112

Posted on 23 February 2015 | 6:37 am


Synthesis of 2-Aryl and 3-Aryl Benzo[b]furan Thioethers Using Aryl Sulfonyl Hydrazides as Sulfenylation Reagents

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00146

Posted on 20 February 2015 | 10:04 pm


Synthesis, Functionalization, and Optical Properties of Chiral Carbazole-Based Diaza[6]helicenes

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The Journal of Organic Chemistry
DOI: 10.1021/jo5024188

Posted on 20 February 2015 | 9:45 pm


Electron-Deficient Heteroarenium Salts: An Organocatalytic Tool for Activation of Hydrogen Peroxide in Oxidations

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The Journal of Organic Chemistry
DOI: 10.1021/jo502865f

Posted on 20 February 2015 | 9:44 pm


Enantiomerically Pure 3-Aryl- and 3-Hetaryl-2-hydroxypropanoic Acids by Chemoenzymatic Reduction of 2-Oxo Acids

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The Journal of Organic Chemistry
DOI: 10.1021/jo502529g

Posted on 20 February 2015 | 4:08 pm


Platinum-Catalyzed Asymmetric Ring-Opening Reactions of Oxabenzonorbornadienes with Phenols

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00065

Posted on 20 February 2015 | 3:08 pm


Diastereoselective Synthesis of Substituted Tetrahydrothiophenes and -thiopyrans via Thia-Prins Cyclization Reaction

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The Journal of Organic Chemistry
DOI: 10.1021/jo502831w

Posted on 20 February 2015 | 2:48 pm


Mechanistic Insights into a BINOL-Derived Phosphoric Acid-Catalyzed Asymmetric Pictet–Spengler Reaction

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The Journal of Organic Chemistry
DOI: 10.1021/jo5028134

Posted on 19 February 2015 | 4:15 pm


Copper-Catalyzed N-Cyanation of Sulfoximines by AIBN

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The Journal of Organic Chemistry
DOI: 10.1021/jo502607c

Posted on 19 February 2015 | 4:15 pm


Origins of Asymmetric Phosphazene Organocatalysis: Computations Reveal a Common Mechanism for Nitro- and Phospho-Aldol Additions

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00063

Posted on 19 February 2015 | 2:45 pm


Synthesis of the Spirocyclic Framework of Sesterterpenoid Natural Products

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The Journal of Organic Chemistry
DOI: 10.1021/jo502897u

Posted on 18 February 2015 | 4:40 pm


A General Method for the One-Pot Reductive Functionalization of Secondary Amides

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The Journal of Organic Chemistry
DOI: 10.1021/jo502929x

Posted on 18 February 2015 | 2:55 pm


One-Pot Synthesis of Aryl Sulfones from Organometallic Reagents and Iodonium Salts

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The Journal of Organic Chemistry
DOI: 10.1021/jo5027518

Posted on 17 February 2015 | 9:52 pm


Palladium-Catalyzed Aryl C(sp2)–H Bond Hydroxylation of 2-Arylpyridine Using TBHP as Oxidant

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00167

Posted on 17 February 2015 | 12:51 pm


Preparation of Tetrasubstituted Olefins Using Mono or Double Aerobic Direct C–H Functionalization Strategies: Importance of Steric Effects

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00148

Posted on 16 February 2015 | 5:00 pm


Ruthenium-Catalyzed Synthesis of 5-Amino-1,2,3-triazole-4-carboxylates for Triazole-Based Scaffolds: Beyond the Dimroth Rearrangement

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The Journal of Organic Chemistry
DOI: 10.1021/jo502577e

Posted on 16 February 2015 | 4:47 pm


Cascade Arylalkylation of Activated Alkenes: Synthesis of Chloro- and Cyano-Containing Oxindoles

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The Journal of Organic Chemistry
DOI: 10.1021/jo502777b

Posted on 16 February 2015 | 2:43 pm


Synthesis of Unusual N-Acylated Aminosugar Fragments of Mycobacterium marinum Lipooligosaccharide IV

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The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00064

Posted on 16 February 2015 | 2:43 pm


Catalyst-Free and Metal-Free Electrophilic Bromoamidation of Unactivated Olefins Using the N-Bromosuccinimide/Sulfonamide Protocol

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The Journal of Organic Chemistry
DOI: 10.1021/jo502416r

Posted on 16 February 2015 | 2:42 pm


Theoretical Study of Mechanism and Stereoselectivity of Catalytic Kinugasa Reaction

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The Journal of Organic Chemistry
DOI: 10.1021/jo502838p

Posted on 13 February 2015 | 8:29 pm


Synthesis of Enantiopure trans-2,5-Disubstituted Trifluoromethylpyrrolidines and (2S,5R)-5-Trifluoromethylproline

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The Journal of Organic Chemistry
DOI: 10.1021/jo502885v

Posted on 13 February 2015 | 8:03 pm


One-Pot Synthesis of Multisubstituted Butyrolactonimidates: Total Synthesis of (?)-Nephrosteranic Acid

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The Journal of Organic Chemistry
DOI: 10.1021/jo5029166

Posted on 13 February 2015 | 4:18 pm


Possibility of [1,5] Sigmatropic Shifts in Bicyclo[4.2.0]octa-2,4-dienes

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The Journal of Organic Chemistry
DOI: 10.1021/jo5027639

Posted on 12 February 2015 | 5:56 pm


Stereoselective Formation of Eight-Membered Rings by Radical Cyclization of Silylenedioxy-Tethered Bis-methacrylate Derivatives

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The Journal of Organic Chemistry
DOI: 10.1021/jo502947k

Posted on 12 February 2015 | 4:08 pm


Transition-Metal-Free Access to Primary Anilines from Boronic Acids and a Common +NH2 Equivalent.

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The Journal of Organic Chemistry
DOI: 10.1021/jo5025078

Posted on 12 February 2015 | 2:33 pm


Visible Light Mediated Cyclization of Tertiary Anilines with Maleimides Using Nickel(II) Oxide Surface-Modified Titanium Dioxide Catalyst

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The Journal of Organic Chemistry
DOI: 10.1021/jo502901h

Posted on 11 February 2015 | 5:18 pm


Potassium Thiocyanate as Source of Cyanide for the Oxidative ?-Cyanation of Tertiary Amines

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The Journal of Organic Chemistry
DOI: 10.1021/jo502846c

Posted on 11 February 2015 | 1:47 pm


Pharmaceutical Process Chemistry: Evolution of a Contemporary Data-Rich Laboratory Environment

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The Journal of Organic Chemistry
DOI: 10.1021/jo502879m

Posted on 9 February 2015 | 5:50 pm


Design and Synthesis of ?-Carboxy Nucleoside Phosphonate Analogues and Evaluation as HIV-1 Reverse Transcriptase-Targeting Agents

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The Journal of Organic Chemistry
DOI: 10.1021/jo502549y

Posted on 9 January 2015 | 7:24 pm





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