BMC Chemical Biology

Current research reports and chronological list of recent articles.


BMC Chemical Biology was an open access journal publishing original peer-reviewed research articles in the application of chemistry to the investigation of biological processes and systems including the biosynthesis and metabolism of natural compounds, drug design and complex molecular rearrangements occurring in living organisms. It is now fused with BMC Biochemistry.

The publisher is the BioMed Central. The copyright and publishing rights of specialized products listed below are in this publishing house. This is also responsible for the content shown.

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Additional research articles see Current Chemistry Research Articles. Magazines with similar content (chemical biology):

 - ACS Chemical Biology,

 - ChemBioChem,

 - Chemical Biology and Drug Design,

 - Current Opinion in Chemical Biology,

 - Nature Chemical Biology.



BMC Chemical Biology - Abstracts



Molecular characterization of protein kinase C delta (PKCδ)-Smac interactions

Protein kinase C δ (PKCδ) is known to be an important regulator of apoptosis, having mainly pro- but also anti-apoptotic effects depending on context. In a previous study, we found that PKCδ interacts with the...
Datum: 23.05.2016


Tubulin is a molecular target of the Wnt-activating chemical probe

In drug discovery research, cell-based phenotypic screening is an essential method for obtaining potential drug candidates. Revealing the mechanism of action is a key step on the path to drug discovery. Howeve...
Datum: 20.05.2016


Identification and characterization of the novel nuclease activity of human phospholipid scramblase 1

Human phospholipid scramblase 1 (hPLSCR1) was initially identified as a Ca2+ dependent phospholipid translocator involved in disrupting membrane asymmetry. Recent reports revealed that hPLSCR1 acts as a multifunc...
Datum: 20.05.2016


Altered activity patterns of transcription factors induced by endoplasmic reticulum stress

The endoplasmic-reticulum (ER) responds to the burden of unfolded proteins in its lumen by activating intracellular signal transduction pathways, also known as the unfolded protein response (UPR). Many signal ...
Datum: 24.03.2016


Conserved motif VIII of murine DNA methyltransferase Dnmt3a is essential for methylation activity

Dnmt3a is a DNA methyltransferase that establishes de novo DNA methylation in mammals. The structure of the Dnmt3a C-terminal domain is similar to the bacterial M. HhaI enzyme, a well-studied prokaryotic DNA meth...
Datum: 22.03.2016






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