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Toxicogenomics
Toxicogenomics is a scientific discipline and research area that studies how the genome is involved in responses to environmental stressors and toxicants. It combines toxicology with genomics to understand the role of gene-environment interactions in diseases, and also offers the opportunity to develop tests that require fewer laboratory animals or cause them less inconvenience
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| ToxFX™ Analysis Suite ... provides a complete toxicogenomics solution to help researchers better understand compound safety issues in early drug discovery and development - [e] |
| Application of toxicogenomics to the endocrine disruption issue Article: Pure Appl. Chem., Vol. 75, Nos. 11–12, pp. 2419–2422, 2003. IUPAC, USA - [e] Database Development in Toxicogenomics: Issues and Efforts Article: Environmental Health Perspectives. EHP, USA - [e] Practical Application of Toxicogenomics in Early Drug Discovery Article, Abbott 2007 - [e] Toxicogenomics in the assessment of immunotoxicity Article, Elsevier, doi 10.1016/j.ymeth.2006.07.010; 2006 - [e] Toxicogenomics: Articles Environmental Health Perspectives Volume 112, Number 16, November 2004 - [e] |
| European Bioinformatics Institute: NET Project The NET Project works to maximize the interactions between Nutrigenomics, Environmental genomics and Toxicogenomics (NET) communities and their collective NETworking capability with EBI groups - [e] Hannover, Germany Chair for Pharmaco- and Toxicogenomics at Hannover Medical School, MHH - [d, e] Netherlands The Netherlands Toxicogenomics Centre, NTC, aims to employ toxicogenomics to increase the basic understanding of toxicological mechanisms towards developing new and better test methods - [e] Toxicogenomics Laboratory Toxic Substances in the Environment. UC Berkeley, USA - [e] |
| National Center for Toxicogenomics Research Center at NIEHS - [e] NCTR Center for Toxicoinformatics The goal of the toxicoinformatics group is to develop methods for the analysis and integration of omics (genomic, transcriptomic, proteomic, and metabolomic) databases with the objective of knowledge discovery and the elucidation of mechanisms of toxicity. FDA, USA - [e] OECD Activities to Explore and Evaluate Regulatory Application of Genomic Methods; Toxicogenomics - [e] Toxicogenomics Research Consortium Enhancement of research in the broad area of environmental stress responses using microarray gene expression profiling - [e] WHO International Programme on Chemical Safety - Toxicogenomics - [e] |
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